Pretransplant Functional Status Predicts Postoperative Morbidity and Mortality after Liver Transplantation in Patients with Cirrhosis.

Background/aims: This study aimed to investigate whether pretransplant frailty can predict postoperative morbidity and mortality after liver transplantation (LT) in patients with cirrhosis.

Methods: We retrospectively reviewed 242 patients who underwent LT between 2018 and 2020 at a tertiary hospital in Korea.

Results: Among them, 189 patients (78.

Clinicopathologic characteristics and long-term prognosis of scirrhous hepatocellular carcinoma.

Background: Clinicopathologic features and long-term outcomes in patients with scirrhous hepatocellular carcinoma (S-HCC) are not fully defined.

Methods: We compared data of 37 patients with S-HCC and 604 with usual HCC (U-HCC) undergoing surgery.

Results: The S-HCC group showed less HBV infection (78.

Salvage treatment with hypofractionated radiotherapy in patients with recurrent small hepatocellular carcinoma.

Purpose: To investigate the rates of tumor response and local control in patients with recurrent small hepatocellular carcinoma (HCC) treated with hypofractionated radiotherapy (RT) as a salvage treatment and to evaluate treatment-related toxicities.

Methods And Materials: Between 2006 and 2009, a total of 20 patients with recurrent small HCC were treated with hypofractionated RT after the failure of previous treatment. The eligibility criteria for hypofractionated RT were as follows: 1) HCC less than 5 cm, 2) HCC not adjacent to critical organs, 3) HCC without portal vein tumor thrombosis, and 4) less than 15% of normal liver volume that would be irradiated with 50% of prescribed dose.

[Clinical features and predictive factors of acute hepatitis A complicated with acute kidney injury].

Background/aims: we assessed the clinical features and prognosis of acute viral hepatitis A (AHA) complicated with acute kidney injury (AKI) and elucidated predictive factors for AKI in patients with AHA.

Methods: we reviewed medical record of 391 patients with AHA admitted at our institution since 2000.

Results: AKI was present in 45 patients (11.

[Antiviral efficacy of lamivudine/adefovir combination therapy in chronic hepatitis b patients with resistance to lamivudine and adefovir consecutively].

Background/aims: The aim of this study was to elucidate the antiviral efficacy of lamivudine (LMV)-adefovir (ADV) combination therapy in chronic hepatitis B patients who showed resistance to LMV and ADV consecutively.

Methods: A retrospective review was performed in eighteen patients with chronic hepatitis B who developed virologic breakthroughs during LMV-ADV sequential mono-therapy and treated with LMV-ADV combination therapy.

Results: The median duration of follow up was 17 months (range, 6-27) after the start of LMV-ADV combination therapy.