Efficacy of Adjunctive Local Antimicrobials to Non-Surgical Periodontal Therapy in Pocket Reduction and Glycemic Control of Patients with Type 2 Diabetes: A Network Meta-Analysis.

Objective: This network meta-analysis [NMA] investigated the efficacy of adjunctive use of subgingivally delivered antimicrobials to non-surgical periodontal therapy [NSPT] in the glycemic control and periodontal pocket depth (PPD) reduction in patients with type 2 diabetes (T2D).

Methods: Seven databases, grey literature, and registry platforms were searched up to February 2024 to identify randomized clinical trials (RCT) fulfilling the eligibility criteria. The risk of bias was assessed through Cochrane's tool (RoB 2).

Influence of periodontal therapy on C-reactive protein level: a systematic review and meta-analysis.

Unlabelled: The influence of oral infections, especially periodontal disease, on systemic diseases has been extensively discussed in the literature. Because periodontal disease is a persistent infection, it promotes an inflammatory response. C-reactive protein is a marker for inflammatory reactions that is frequently studied, since elevated levels of this protein are related to coronary events.

Relationship between glycemic subsets and generalized chronic periodontitis in type 2 diabetic Brazilian subjects.

Objective: The aim of the present study was to evaluate the relationship between glycemic subsets and clinical periodontal conditions in type 2 diabetic Brazilians with generalized chronic periodontitis.

Design: Ninety-one Brazilians with type 2 DM and generalized chronic periodontitis were involved in this study. The clinical examination included full-mouth assessment of plaque index (PI), bleeding on probing (BoP), probing depth (PD), suppuration (SUP), clinical attachment level (CAL) and number of remaining teeth.

Cigarette smoke combined with staining beverages decreases luminosity and increases pigmentation in composite resin restorations.

This study evaluated the effect of cigarette smoke combined or not with colored beverages on the color change of a composite resin before and after repolishing procedures. Composite specimens were allocated into six groups (N = 10): 1) control (no colorant); 2) cigarette smoke; 3) coffee; 4) coffee and cigarette smoke; 5) red wine; and 6) red wine and cigarette smoke. During 21 days, groups 2, 4, and 6 were exposed daily to the smoke from 20 cigarettes, and groups 3, 4, 5, and 6 were immersed in coffee or red wine for 4 minutes each day.

Impact of periodontitis on the diabetes-related inflammatory status.

Wide-ranging activation of the innate immune system causing chronic low-grade inflammation is closely involved not only in the pathogenesis of type 2 diabetes mellitus and its complications, through an ongoing cytokine-induced acute-phase response, but also in the pathogenesis of periodontal diseases, whereby cytokines play a central role in the host's response to the periodontal biofilm. Although there is extensive knowledge about the pathways through which diabetes affects periodontal status, less is known about the impact of periodontal diseases on the diabetes-related inflammatory state. This review attempts to explain the immunobiological connection between periodontal diseases and type 2 diabetes mellitus, exploring the mechanisms through which periodontal infection can contribute to the low-grade general inflammation associated with diabetes (thus aggravating insulin resistance) and discussing the impact of periodontal treatment on glycemic control in people living with both diabetes and periodontal disease.

Morphologic texture characterization allied to cigarette smoke increase pigmentation in composite resin restorations.

Statement Of The Problem: The staining effect of tobacco smoke on resin color is clinically observed. However, there is no evidence determining whether this staining is increased on texturized surfaces or if the color change is superficial and can be removed by repolishing procedures.

Objective: To evaluate the effect of tobacco smoke on the color of a composite with smooth or texturized surfaces, before and after repolishing.

Flavoring agents present in a dentifrice can modify volatile sulphur compounds (VSCs) formation in morning bad breath.

This study aimed to evaluate the effects of a flavor-containing dentifrice on the formation of volatile sulphur compounds (VSCs) in morning bad breath. A two-step, blinded, crossover, randomized study was carried out in 50 dental students with a healthy periodontium divided into two experimental groups: flavor-containing dentifrice (test) and non-flavor-containing dentifrice (control). The volunteers received the designated dentifrice and a new toothbrush for a 3 X/day brushing regimen for 2 periods of 30 days.

Use of 0.1% chlorine dioxide to inhibit the formation of morning volatile sulphur compounds (VSC).

The aim of this study was to evaluate the VSC-inhibiting effect of a commercially available mouthrinse (0.1% chlorine dioxide) when compared to its placebo. A 2-step double blind, crossover, randomised study was conducted with 14 dental students with healthy periodontium, who refrained from any mechanical plaque and tongue coating control during two 4-day experimental periods.

Effect of cigarette smoke inhalation and estrogen deficiency on bone healing around titanium implants: a histometric study in rats.

Background: It has been shown that cigarette smoke inhalation (CSI) and estrogen deficiency (OVX) may affect bone quality around titanium implants; however, their association has not been evaluated. Therefore, this study aimed to verify the effects of CSI associated with OVX on bone healing around titanium implants.

Methods: The tibia surface of 45 female Wistar rats was surgically exposed, and screw-shaped titanium implants were placed.

Importance of differential diagnosis in endodontic-periodontal lesions: case reports.

Two case reports are presented in which the radiographic characteristics induced initially incorrect diagnoses. Only after combined clinical and radiographic examinations were the appropriate diagnoses achieved. This article demonstrates the need for close cooperation between periodontists and endodontists to diagnose periradicular lesions accurately.

Immunosuppressant therapy and bone loss in ligature-induced periodontitis--a study in rats.

Immunosuppressive agents have been recognized as a factor affecting the soft tissues of the periodontium. However, little is known about their effect on periodontitis progression. The aim of the present study was to investigate the influence of cyclosporin A (CsA) administration, associated or not with nifedipine, on the bone loss resulting from a ligature-induced periodontitis in rats.

Reattachment of an autogenous tooth fragment in a fracture with biologic width violation: a case report.

An 11-year-old patient that fractured her maxillary left central incisor is presented. The fracture involved two thirds of the crown, compromising the pulp, and extended subgingivally on the palatal aspect, invading the biologic width. The procedure used to repair the fracture included flap surgery with a slight ostectomy and endodontic treatment.

Effect of bismuth subgallate (local hemostatic agent) on wound healing in rats. Histological and histometric findings.

The aim of this research was to evaluate the effect of bismuth subgallate on wound healing. In 40 Wistar rats, two standard wounds (3.5 mm x 2 mm) were made using a biopsy punch on the back of each animal.