Publications by authors named "Gessica Lorena Gamarra"
Article Synopsis
- - Clostridioides difficile (CD) is the leading cause of diarrhea in healthcare settings, and its severity has grown due to more aggressive strains.
- - The primary factor for CD's virulence is toxin production, but the study found other important genetic factors contributing to its virulence.
- - Researchers sequenced 38 strains and found most were toxigenic, with some lacking genes related to adhesion, highlighting the need to explore other virulence factors for a better understanding of CD.
Little is known about the role of lineage of strains of Clostridioides difficile (CD) on the clinical presentation of CD infection (CDI) in Latin America, especially regarding the treatment response. We conducted a multicenter, prospective study to investigate the predictive factors and treatment outcomes of CDI in hospitalized patients and to performed phenotypical and molecular characterization of CD strains. A total of 361 diarrheic patients at 5 hospitals from different regions of the country were enrolled.
View Article and Find Full Text PDFEpidemiological data on CD infection (CDI) in Latin American are scarce. CDI prevalence and strains characterization were prospectively evaluated in 5 Brazilian hospitals from different regions. Prevalence rates of CDI were 15%, ranging from 0 to 37%.
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