Publications by authors named "Gesa Kaltenecker"
Article Synopsis
- Induced pluripotent stem cell-derived mesenchymal stromal cells (iMSCs) and their extracellular vesicles (iMSC-EVs) are being evaluated as alternatives to traditional primary mesenchymal stromal cells (hUCMSCs) for use in advanced therapies.
- The study found that iMSCs effectively regulate immune responses, showing similar abilities to hUCMSCs in controlling lymphocyte growth and promoting an anti-inflammatory environment.
- Furthermore, iMSC-EVs demonstrated both immunomodulatory and regenerative properties, with enhanced effects observed when iMSCs were treated with pro-inflammatory cytokines, highlighting their potential as therapeutic options.
We present novel workflows for Q-FISH nanoscopy with the potential for prognostic applications and resolving novel chromatin compaction changes. DNA-fluorescence in situ hybridization (DNA-FISH) is a routine application to visualize telomeres, repetitive terminal DNA sequences, in cells and tissues. Telomere attrition is associated with inherited and acquired diseases, including cancer and cardiomyopathies, and is frequently analyzed by quantitative (Q)-FISH microscopy.
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