Publications by authors named "Gersson Vasquez-Machado"

Article Synopsis
  • The first draft genome assembly for a key fish species in Colombia's Prochilodontidae family has been created, with a size of 1.2-Gb and a notable 42.0% GC content.
  • The genome features 34,725 identified nuclear genes and shows high completeness, indicating it has similar genetic profiles to related species like blind cave fish and red piranha.
  • This assembly not only confirms the species' taxonomic classification but also serves as a valuable genetic resource for sustainable fish management in Colombia and contributes to research in South American fish genomics.
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Streptococcosis in tilapia Oreochromis sp. is possibly the most important bacterial disease for fish production worldwide. In Colombia, streptococcosis is caused by Streptococcus agalactiae (GBS), but in other countries, Streptococcus iniae is also involved.

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A nanomotor-based strategy for rapid single-step intracellular biosensing of a target miRNA, expressed in intact cancer cells, at the single cell level is described. The new concept relies on the use of ultrasound (US) propelled dye-labeled single-stranded DNA (ssDNA)/graphene-oxide (GO) coated gold nanowires (AuNWs) capable of penetrating intact cancer cells. Once the nanomotor is internalized into the cell, the quenched fluorescence signal (produced by the π-π interaction between GO and a dye-labeled ssDNA) is recovered due to the displacement of the dye-ssDNA probe from the motor GO-quenching surface upon binding with the target miRNA-21, leading to an attractive intracellular "OFF-ON" fluorescence switching.

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