Publications by authors named "Gerrit D Wilkens"
Article Synopsis
- Liposomes, which are small vesicles used in various applications, are usually produced in large sizes with significant variability, while nature offers smaller, functional systems that are hard to replicate synthetically.
- The development of a DNA origami "bubble blower" has been introduced, which is a nanoscale ring designed to facilitate and control the creation of these smaller liposomes.
- This innovative approach enhances existing methods by allowing for a greater range of compatible detergents and integrating support for potential semi-automated production in laboratories.
DNA origami is a widely used DNA nanotechnology that allows construction of two-dimensional and three-dimensional nanometric shapes. The designability and rigidity of DNA origami make it an ideal material for construction of topologically linked molecules such as catenanes, which are attractive for their potential as motors and molecular machines. However, a general method for production of topologically linked DNA origami has been lacking.
View Article and Find Full Text PDFThe DNA origami technique allows the facile design and production of three-dimensional shapes from single template strands of DNA. These can act as functional devices with multiple potential applications but are constrained by practical limitations on size. Multi-functionality could be achieved by connecting together distinct DNA origami modules in an ordered manner.
View Article and Find Full Text PDFDNA nanotechnology research has long-held promise as a means of developing functional molecules capable of delivery to cells. Recent advances in DNA origami have begun to realize this potential but is still at the earliest stage and a number of hurdles remain. This review focuses on progress in addressing these hurdles and considers some of the challenges still outstanding.
View Article and Find Full Text PDF