Publications by authors named "Gerran Salto"

Article Synopsis
  • The study investigates the factors contributing to sex differences in heart failure phenotypes, focusing on genetic and environmental influences on cardiac structure and function.
  • Researchers analyzed data from 5,674 participants in the Framingham Heart Study to determine the heritability of various echocardiographic traits.
  • Results showed significant heritability for both genders, but with notable sex-based differences in genetic and environmental correlations among cardiac traits, suggesting different pathways leading to heart failure in men and women.
View Article and Find Full Text PDF

Purpose Of Review: Anatomical segmentation has played a major role within clinical cardiology. Novel techniques through artificial intelligence-based computer vision have revolutionized this process through both automation and novel applications. This review discusses the history and clinical context of cardiac segmentation to provide a framework for a survey of recent manuscripts in artificial intelligence and cardiac segmentation.

View Article and Find Full Text PDF

Objective: Established preclinical imaging assessments of heart failure (HF) risk are based on macrostructural cardiac remodelling. Given that microstructural alterations may also influence HF risk, particularly in women, we examined associations between microstructural alterations and incident HF.

Methods: We studied N=2511 adult participants (mean age 65.

View Article and Find Full Text PDF

Background: Immune-inflammatory myocardial disease contributes to multiple chronic cardiac processes, but access to non-invasive screening is limited. We have previously developed a method of echocardiographic texture analysis, called the high-spectrum signal intensity coefficient (HS-SIC) which assesses myocardial microstructure and previously associated with myocardial fibrosis. We aimed to determine whether this echocardiographic texture analysis of cardiac microstructure can identify inflammatory cardiac disease in the clinical setting.

View Article and Find Full Text PDF

The heart-liver axis is of growing importance. Previous studies have identified independent association of liver dysfunction and fibrosis with adverse cardiac outcomes, but mechanistic pathways remain uncertain. We sought to understand the relations between the degree of hepatic fibrosis identified by the Fibrosis-4 (Fib-4) risk score and comprehensive cardiac MRI (CMR) measures of subclinical cardiac disease.

View Article and Find Full Text PDF

Echocardiographic imaging has been acquired in historical longitudinal cohorts of cardiovascular disease. Many cohorts were established prior to digital recording of echocardiography, and thus have preserved their archival imaging on Video Home System (VHS) tapes. These tapes require large physical storage space, are affected by physical degradation, and cannot be analyzed using modern digital techniques.

View Article and Find Full Text PDF