Publications by authors named "Geron Bindseil"
Design and construction of a gradient coil for high resolution marmoset imaging.
Biomed Phys Eng Express
July 2020
Article Synopsis
- A new gradient coil with second and third order shims was created for a 9.4 T small animal MRI, specifically designed for marmoset imaging.
- The design utilized advanced techniques to minimize power in conducting surfaces, achieving high efficiency of 1.5 mT/mA while ensuring gradient uniformity within 5% in the designated imaging area.
- Innovative cooling systems were introduced, enabling the coil to function at 100 A RMS with a temperature rise of less than 30°C, which is 25% of its maximum current capacity.
Background: Early detection of Alzheimer's disease (AD) pathology is a serious challenge for both diagnosis and clinical trials. The aspartyl protease, Cathepsin D (CatD), is overexpressed in AD and could be a biomarker of disease. We have previously designed a unique contrast agent (CA) for dual-optical and magnetic resonance imaging of the activity of the CatD class of enzymes.
View Article and Find Full Text PDFCombining positron emission tomography and MRI modalities typically requires using either conventional MRI with a MR-compatible positron emission tomography system or a modified MR system with conventional positron emission tomography. A feature of field-cycled MRI is that all magnetic fields can be turned off rapidly, enabling the use of conventional positron emission tomography detectors based on photomultiplier tubes. In this demonstration, two photomultiplier tube-based positron emission tomography detectors were integrated with a field-cycled MRI system (0.
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