Acute Glaucoma Following Internal Carotid Artery Stenting: A Rare But Serious Complication of Ocular Ischemic Syndrome.

Acute glaucoma following carotid artery recanalization is a rare but severe complication of underlying ocular ischemic syndrome. We present a case of a 71-year-old woman with ocular ischemic syndrome and severe stenosis of the right internal and external carotid artery undergoing carotid artery stenting. Immediate postprocedural angiography showed pronounced reperfusion of the ophthalmic artery.

Visualization of Liliequist's membrane prior to endoscopic third ventriculostomy.

Purpose: Endoscopic third ventriculostomy (ETV) is an effective treatment in patients with obstructive hydrocephalus caused by aqueductal stenosis. Operative failure may occur if an unnoticed membrane below the floor of the third ventricle is present, such as Liliequist's membrane (LM). To analyze how often LM can be visualized by high-resolution heavily T2-weighted 3D-MRI prior to ETV, and to find out potential reasons for diagnostic failure.

Focal subarachnoid haemorrhage mimicking transient ischaemic attack--do we really need MRI in the acute stage?

Background: Acute non-traumatic focal subarachnoid haemorrhage (fSAH) is a rare transient ischaemic attack (TIA)-mimic. MRI is considered to be indispensable by some authors in order to avoid misdiagnosis, and subsequent improper therapy. We therefore evaluated the role of CT and MRI in the diagnosis of fSAH patients by comparing our cases to those from the literature.

Mechanical thrombectomy in basilar artery thrombosis: technical advances and safety in a 10-year experience.

Purpose: Multiple endovascular devices have been used for mechanical thrombectomy (MT) in basilar artery occlusion (BAO) for >10 years. Based on a single-center experience during the course of one decade, we present data on safety and efficacy of previous MT devices compared with modern stent retriever and suction thrombectomy.

Materials And Methods: Eighty-one patients (29 women, 52 men, mean age 61.

Current strategies in the diagnosis of diffuse large B-cell lymphoma of the central nervous system.

Lymphomas can arise within the central nervous system (CNS) as primary CNS lymphoma (PCNSL) typically involving the brain and less often the leptomeninges, eyes, and spinal cord. In contrast to PCNSL, secondary CNS lymphoma (SCNSL) is considered to originate as quasi metastasis from systemic lymphoma spreading to the CNS. Both types of CNS lymphomas are predominantly tumours of the diffuse large B-cell type and represent aggressive diseases necessitating a rapid diagnosis.

Management of patients with transient ischemic attack is safe in an outpatient clinic based on rapid diagnosis and risk stratification.

Background: Transient ischemic attack (TIA) patients are at high risk of short-term stroke, myocardial infarction and vascular death. Stroke risk is reduced by immediate treatment initialization. Stroke unit treatment is recommended for TIA patients.

MRI patterns in recurrence of primary CNS lymphoma in immunocompetent patients.

Purpose: Primary CNS lymphomas (PCNSL) are highly malignant non-Hodgkin's B-cell lymphoma restricted to the CNS. While MRI features of PCNSL at initial presentation have been comprehensively described, literature on MRI-characteristics at relapse is sparse. The purpose of this study was to investigate anatomic location and contrast enhancement patterns at PCNSL recurrence by cranial MRI.

Three-dimensional constructive interference in steady-state magnetic resonance imaging in obstructive hydrocephalus: relevance for endoscopic third ventriculostomy and clinical results.

Object: Endoscopic third ventriculostomy is the treatment of choice in patients with obstructive hydrocephalus caused by aqueductal stenosis. The authors examined the clinical course and results of surgical treatment for obstructive hydrocephalus with pre- and postoperative refined constructive interference in steady-state (CISS) MR imaging.

Methods: Forty patients with obstructive hydrocephalus underwent pre- and postoperative 3D-CISS imaging and clinical evaluation.

Continuous intra-arterial nimodipine for the treatment of cerebral vasospasm.

Two patients with refractory symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) were treated by continuous intra-arterial nimodipine infusion via a catheter placed in the internal carotid artery or vertebral artery for 3 and 12 days, respectively. Recovery of the neurological deficits, normalization of MR perfusion, a decrease in the elevated mean flow velocity measured by transcranial duplex sonography, and angiographic recanalization were observed. Continuous intra-arterial nimodipine might be a treatment option in severe refractory vasospasm following SAH.

Treatment of wide-necked intracranial aneurysms with a novel self-expanding two-zonal endovascular stent device.

Introduction: Endovascular treatment of intracerebral wide-necked aneurysms carries the risk of incomplete embolisation and recanalisation of the aneurysm as well as coil protrusion into the parent artery and embolic complications. We present preliminary results with the placement of a novel tightly braided stent across the aneurysm neck which might lead to thrombosis of these aneurysms.

Methods: A bifurcation artery aneurysm was created in a male New Zealand White Rabbit.

Functional outcome after severe cerebral venous thrombosis.

Severe cerebral venous thrombosis (CVT) is a rare cerebrovascular condition which in the more severe cases warrants intensive care treatment. While the outcome in the majority of uncomplicated CVT cases is good, it may be fatal in more affected patients. We provide long-term functional and quality of life (QOL) outcome data in the form of a retrospective analysis of 10 patients admitted to a neurological ICU with severe CVT.

A multicenter, site-independent, blinded study to compare the diagnostic accuracy of contrast-enhanced magnetic resonance angiography using 1.0M gadobutrol (Gadovist) to intraarterial digital subtraction angiography in body arteries.

Purpose: Prospective evaluation of diagnostic accuracy of single field-of-view contrast-enhanced MR Angiography (ceMRA) with 1.0M gadobutrol compared to intraarterial DSA in body arteries.

Materials And Methods: In an European multicenter study 179 patients underwent ceMRA and DSA.

Stent-angioplasty of intracranial vertebral and basilar artery stenoses in symptomatic patients.

Background: To present our two-center treatment results with stent angioplasty of intracranial vertebrobasilar stenoses in symptomatic patients.

Material And Methods: Between 2001 and 2003, 21 patients with 22 stenoses, refractory to medical therapy, who underwent elective stenting of intracranial vertebrobasilar stenoses were retrospectively analyzed. All patients had ischemic events clinically referable to the stenoses.

Treatment of vertebrobasilar occlusion by using a coronary waterjet thrombectomy device: a pilot study.

Background And Purpose: Despite improved patient outcomes because of intraarterial fibrinolysis, vertebrobasilar thromboembolism remains a fatal disease with a death rate of more than 50%. The outcome depends on the success of recanalization. Fibrinolysis achieves recanalization in only 50%-70% of the cases.

Extent of spontaneous cross-flow via the anterior communicating artery in steno-occlusive carotid artery disease.

Purpose: Our purpose was to evaluate the agreement of transcranial color-coded duplex sonography (TCCS) measurements and intra-arterial digital subtraction angiography (DSA) findings in determining the extent of spontaneous cross-flow via the anterior communicating artery (AcoA) in patients with internal carotid artery (ICA) stenosis.

Methods: Thirty adult patients with suspected uni- or bilateral high-grade carotid artery stenosis were prospectively examined by DSA and angle-corrected TCCS. The extent of cross-flow was determined considering retrograde flow in the ipsilateral anterior cerebral artery (ACA) and sideto-side differences of the A1-segments of the ACA and middle cerebral arteries (MCAs) by both techniques.

Measuring carotid artery stenosis--comparison of postmortem arteriograms with the planimetric gold standard.

Objective: Five different calliper methods for assessing the degree of carotid artery stenosis and visual estimation ("eyeballing") of postmortem carotid arteriograms were compared with the planimetric gold standard of the area reduction at the site of the stenosis.

Methods: During autopsy 53 carotid specimens were removed in toto from 31 neurological patients. Carotid arteries were ligated and redistended to a physiological degree for standardised three-plane arteriography.

Simultaneous ischemic and neurotoxic brain damage after coronary angiography.

Transient cortical blindness following intra-arterial catheter angiography is a known rare complication. We report the case of a 56-year-old man who suffered from transient cortical blindness and neuropsychological deficits after coronary angiography. Serial CT scans revealed reversible pathologic parenchymal contrast enhancement of the right occipital lobe as well as left middle cerebral artery infarction at the same time.

Does ultrasound contrast agent improve the diagnostic value of colour and power Doppler sonography in superficial lymph node enlargement?

Objective: to analyse whether ultrasound contrast agent (UCA) improves the diagnostic accuracy to differentiate between benign and malignant superficial lymph node enlargement by using colour-coded duplex sonography (CCDS) and power Doppler (PD).

Methods: 32 patients with suspected malignant superficial lymph node enlargement prospectively underwent standardised ultrasound examinations using B-mode sonography and native and contrast-enhanced CCDS and PD immediately before biopsy. Solbiati-Index (longitudinal-transverse diameter ratio) and intranodal flow patterns by using different vascularisation types were assessed.

Image quality of the temporal bone window examined by transcranial Doppler sonography and correlation with postmortem computed tomography measurements.

Background And Purpose: The major limitation of native transcranial colour-coded duplex sonography (TCCS) in older stroke patients is the relatively frequent occurrence of an insufficient temporal window. Our goal was to investigate the relationship between the in vivo Doppler ultrasound image quality of the temporal bone, and computed tomography (CT)-determined thickness, density, and homogeneity of cadaver temporal bone.

Methods: Thirty-three moribund neurological patients who eventually died were examined by TCCS using the transtemporal approach.

On the origin of microembolic signals--a clinical and postmortem study.

Background And Purpose: Clinically silent circulating microembolic signals (MES) can be identified by transcranial Doppler ultrasound (TCD). It is not yet clear whether their occurrence is always linked to the presence of embolic sources.

Methods: 24 terminally ill patients (7 women, 17 men; mean age 68 years) were investigated by TCD of the middle cerebral arteries.