Publications by authors named "German A Garcia-Ferrando"
Background: Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by a heterogeneous and abnormal vascularity. Subtypes of vascular habitats within the tumor and edema can be distinguished: high angiogenic tumor (HAT), low angiogenic tumor (LAT), infiltrated peripheral edema (IPE), and vasogenic peripheral edema (VPE).
Purpose: To validate the association between hemodynamic markers from vascular habitats and overall survival (OS) in glioblastoma patients, considering the intercenter variability of acquisition protocols.
Background: Neuroimaging analysis is currently crucial for an early assessment of glioblastoma, to help improving treatment and tumor follow-up. To this end, multiple functional and morphological MRI sequences are usually employed, requiring the development of automated tools capable to extract the relevant information from these sources. In this work we present ONCOhabitats (https://www.
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- * Hemodynamic tissue signature (HTS) markers, derived from MR perfusion images, offer valuable insights into GBM's intra-tumor variations and are significantly associated with patient survival rates.
- * The study shows that incorporating HTS markers into traditional prognostic models, which mainly rely on clinical and demographic data, significantly improves their predictive accuracy and is available for research at a designated website.