Publications by authors named "Gerlin Varghese"
Ralstonia species are recently emerging as pathogens of human importance. This study was performed to assess the distribution of Ralstonia species among bacteremia patients and the clinical and demographical factors of these patients. This retrospective observational study was performed in the Microbiology Department of a tertiary care center in North India from April 2022 to April 2024.
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- Trauma and accidental injuries are a major global health concern, with India experiencing the highest road accident deaths, accounting for 11% of the world's total.
- A study from January 2023 to January 2024 analyzed wound samples from road traffic accident (RTA) patients in a northern Indian tertiary care center to assess bacterial contamination and antibiotic susceptibility.
- Out of 189 samples, 52.38% showed microbial growth, predominantly Gram-negative bacilli, with none being resistant to colistin; 26.45% of patients developed sepsis, linked to raised procalcitonin levels and low Glasgow Coma Scale scores.
Blood stream infection with Microbacterium species in humans is rare and frequently linked to the presence of immunosuppressed conditions such as patients on chemotherapy or corticosteroids. Presence of indwelling catheters is also a potential risk factor for M. aurum infection.
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- Leuconostoc species, particularly L. lactis, are significant causes of infections in immunocompromised patients, prompting this study to analyze their characteristics in a tertiary care center in northern India.
- Over a two-year period, only 0.21% of 6,742 blood cultures tested positive for L. lactis, mainly affecting younger males (average age 34) with underlying health issues and intravascular devices.
- All L. lactis isolates were found to be sensitive to multiple antibiotics, but the bacteremia resulted in five patient deaths, highlighting the need for rapid identification and targeted treatment for these infections.
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- The study examined antimicrobial resistance patterns of Salmonella enterica serovars involved in bloodstream infections in Northern India from January 2021 to April 2023.
- It identified 32 serovars, with Salmonella Typhi being the most common; all isolates were sensitive to several antibiotics but showed high resistance to pefloxacin and nalidixic acid.
- The findings emphasize the need for ongoing monitoring of Salmonella resistance to inform treatment strategies and manage the risk of developing resistant strains.
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- Weissella species are often confused with Lactobacillus or Leuconostoc due to similar Gram-staining and vancomycin resistance, prompting this study on their infection patterns.
- Conducted between January 2021 and August 2023, the research focused on 13 patients at a tertiary care center, revealing a male predominance and identifying Weissella confusa as the most common isolate.
- Main risk factors included anemia and prolonged hospital stays, with all isolates showing sensitivity to several antibiotics, though Weissella infections led to three patient fatalities, highlighting the need for prompt identification to ensure proper treatment.
Background And Objective: Amoebic liver abscess (ALA) and pyogenic liver abscesses (PLA) are the most common causes of liver abscess in developing and developed countries, respectively. Although incidence of liver abscess is low, but mortality is high amongst the patients due to delayed diagnosis. The study was done to find out the prevalence of amoebic and PLA among patients of liver abscess.
View Article and Find Full Text PDFKocuria species are normal commensals of the skin that have been found in various environmental niches and are usually considered nonpathogenic. However, according to recent literature, Kocuria spp. have been associated with human infections.
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