Publications by authors named "Gerlando Preti"

Background: Prompt reperfusion is critical for patients with ST-segment elevation myocardial infarction (STEMI) to improve outcomes. Yet, variability in regional healthcare delivery may influence treatment times and patient outcomes. We thus aimed at evaluating differences in management and outcomes of STEMI patients across Northern, Central, and Southern Italy, focusing on time-dependent reperfusion and in-hospital logistics.

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Article Synopsis
  • The resorbable magnesium scaffold (RMS) is being studied for its safety and long-term effectiveness in patients undergoing bioresorbable scaffold implantation, amid conflicting results from earlier research.
  • In a multicenter study in Italy, 543 patients were followed for a minimum of one year, with strict criteria for patient selection and RMS implantation techniques.
  • Results showed a low occurrence of serious complications at one year, with 3.5% of patients experiencing major adverse events, suggesting that RMS is a safe option that could lead to renewed interest in scaffold technology if further confirmed by randomized trials.
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Background: Little evidence to date has described the feasibility and diagnostic accuracy of coronary computed tomography angiography (CCTA) with noninvasive fractional flow reserve (CT-FFR) in coronary vessels with resorbable magnesium scaffold (RMS).

Methods: The SHERPA-MAGIC is a prospective study enrolling patients receiving RMS. The present analysis considered patients undergoing CCTA 18 months after the index procedure.

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  • * Out of 406 patients, 56.4% were treated for cardiogenic shock (CS) and 43.6% for high-risk percutaneous coronary intervention (HR-PCI); DRCs occurred in 25.6% of patients, with a significantly higher incidence in the CS group (37.1%) compared to the HR-PCI group (10.7%).
  • * The findings suggest that while CS is a strong predictor of DRCs, DRCs themselves do not independently predict
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  • The study aimed to evaluate the safety and feasibility of mini-invasive radial balloon aortic valvuloplasty (BAV), along with its effects on quality of life and frailty in patients undergoing transcatheter aortic valve implantation (TAVI).
  • A total of 330 patients were included, with BAV performed successfully in 314, showing no major bleeding and a minor bleeding rate of 1.8%; both quality of life and frailty improved noticeably after 30 days.
  • The findings indicated that patients who improved their frailty status had better long-term survival rates after TAVI, while those with persistent frailty had significantly worse outcomes.
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