Longitudinal analysis of microcirculatory parameters in gingival tissues after tooth extraction in patients with different risk profiles for wound healing disorders - a pilot study.

Objectives: We aimed to establish a risk profile for intraoral wound healing disorders based on measurements of microcirculation in gingival tissues.

Materials And Methods: Oxygen saturation (SO and blood flow in gingival tissues were measured with tissue spectrometry and laser doppler spectroscopy in 37 patients before/after tooth extractions. Patients were assigned to four groups: anamnestically and periodontally healthy patients (n = 7), anamnestically healthy but suffering from periodontitis (n = 10), anamnestically healthy but smoking and suffering from periodontitis (n = 10) and suffering from diabetes and periodontitis (n = 10).

Determination of baseline alveolar mucosa perfusion parameters using laser Doppler flowmetry and tissue spectrophotometry in healthy adults.

To determine the baseline perfusion parameters of the alveolar mucosa using laser Doppler flowmetry and tissue spectrophotometry (LDF-TS) in healthy adults. Forty-two healthy adult subjects of either sex were tested. The perfusion of the alveolar mucosa was evaluated using a laser Doppler flowmetry and tissue spectrophotometry using O2C 'oxygen to see' device.

Sika deer antler as a novel model to investigate dental implant healing: A pilot experimental study.

Dental implants are important tools for restoring the loss of teeth. The rapid growth and periodic regeneration of antlers make Sika deer a good and less invasive alternative model for studying bone remodelling in mammals. We developed a special loading device for antlers and analysed the bone reaction around unloaded implants and under immediate loading conditions until osseointegration occurred.

Biomechanical characteristics of immediately loaded and osseointegration dental implants inserted into Sika deer antler.

This study aimed to compare biomechanical characteristics of immediately loaded (IL) and osseointegrated (OS) dental implants inserted into Sika deer antler and lay a foundation for developing an alternative animal model for dental implants studies. Two implants per antler were inserted. One implant was loaded immediately via a self-developed loading device; the other was submerged and unloaded as control.

Characterization of a diet-induced obesity rat model for periodontal research.

Objectives: Obesity is associated with periodontitis, but the mechanisms underlying this association have yet to be unraveled. The present investigation was to evaluate a common rat model, in which obesity is induced by high-fat, high-sucrose diet (HFSD), for its applicability in periodontal research.

Materials And Methods: Ten male Wistar rats were fed a 3-month HFSD along with a matching control group.

Numerical investigation of bone remodelling around immediately loaded dental implants using sika deer (Cervus nippon) antlers as implant bed.

This study combines finite element method and animal studies, aiming to investigate tissue remodelling processes around dental implants inserted into sika deer antler and to develop an alternative animal consuming model for studying bone remodelling around implants. Implants were inserted in the antlers and loaded immediately via a self-developed loading device. After 3, 4, 5 and 6 weeks, implants and surrounding tissue were taken out.

Incidence and severity of gingival invaginations associated with early versus late initiation of orthodontic space closure after tooth extraction : A multicenter pilot and randomized controlled trial.

Objective: Gingival invaginations are a common side effect of orthodontic extraction-space closure. The timing of initiating the closure of an extraction space varies greatly in clinical practice. In this multicenter pilot and randomized controlled trial, we prospectively investigated whether initiating space closure in the early stage of wound healing would benefit the incidence and severity of invaginations developing in the extraction sites.

Immunohistochemical analysis of the gingiva with periodontitis of type I plasminogen deficiency compared to gingiva with gingivitis and periodontitis and healthy gingiva.

Objective: Type I plasminogen deficiency (Plgdef) is an uncommon chronic inflammation of mucous membranes. Gingival enlargements usually proceed with progressive periodontal destruction and tooth-loss. Plasmin(ogen)-independent enzymatic mechanisms for fibrin clearance have already been discussed in the literature.

Long-term effects of vertical bone augmentation: a systematic review.

Unlabelled: Extraction, periodontitis, or trauma can cause a reduction on the alveolar ridge. This could result in an insufficient alveolar bone width and height. Different techniques of vertical bone augmentation are described in literature.

Recurrent squamous odontogenic tumor: A case report and review of the literature.

Squamous odontogenic tumors (SOTs) are benign, locally infiltrative neoplasms that localize to the periodontium. In total, <50 cases have been reported since the first description of SOTs in 1975. Although the exact etiology of SOTs is unknown, the tumors are considered to derive from the epithelial cell rests of Malassez.

The Use of High-Frequency Ultrasound in the Measurement of Thickness of the Maxillary Attached Gingiva.

Purpose: Ultrasonography has been extensively explored in dentistry because of its several diagnostic advantages. The purpose of this study was to determine the thickness of the maxillary attached gingiva with the use of a high-frequency ultrasound in subjects with sex-, age- and smoking-related differences.

Materials And Methods: A total of 100 healthy subjects (70 women and 30 men, age range: 18 to 55 years) were included.

Correlation between peri-implant sulcular fluid rate and expression of collagenase2 (MMP8).

Objectives: The rapidly increasing numbers of inserted dental implants and the growing incidence of peri-implant mucositis and peri-implantitis with the current absence of reliable disease risk prediction highlight the importance of early and sensitive diagnosis of possible disease progression. The aim of this study is to assess quantitative and qualitative analysis of peri-implant sulcular fluid (PISF) during implant maintenance control and to identify whether there is a positive correlation and statistical significance between peri-implant sulcular fluid volume results and collagenase2 level obtained from both superficial and fundus area of peri-implant sulcus.

Material And Method: Twenty-seven implants from patients under recall provided peri-implant sulcular fluid volume samples, which were collected with the Periotron 8000 micro-moisture meter, and collagenase2 levels, which were assessed using dentoTest aMMP8.

Regulation of NAMPT in human gingival fibroblasts and biopsies.

Adipokines, such as nicotinamide phosphoribosyltransferase (NAMPT), are molecules, which are produced in adipose tissue. Recent studies suggest that NAMPT might also be produced in the tooth-supporting tissues, that is, periodontium, which also includes the gingiva. The aim of this study was to examine if and under what conditions NAMPT is produced in gingival fibroblasts and biopsies from healthy and inflamed gingiva.

Implant-supported mandibular overdentures and cortical bone formation: clinical and radiographic results.

Purpose: The aim of this study was to evaluate the hard and soft tissue parameters around implants supporting overdentures and the possible influence of increased periimplant bone density (IPBD) on implant success.

Materials And Methods: A total of 44 dental implants placed in the mandible of 12 patients were included in the study. Implants were divided in 2 groups in relation to the optically detected IPBD.

Comparison of the accuracy of cone beam computed tomography and medical computed tomography: implications for clinical diagnostics with guided surgery.

Purpose: This study compared the accuracy of cone beam computed tomography (CBCT) and medical-grade CT in the context of evaluating the diagnostic value and accuracy of fiducial marker localization for reference marker-based guided surgery systems.

Materials And Methods: Cadaver mandibles with attached radiopaque gutta-percha markers, as well as glass balls and composite cylinders of known dimensions, were measured manually with a highly accurate digital caliper. The objects were then scanned using a medical-grade CT scanner (Philips Brilliance 64) and five different CBCT scanners (Sirona Galileos, Morita 3D Accuitomo 80, Vatech PaX-Reve3D, 3M Imtech Iluma, and Planmeca ProMax 3D).

Determination of the frictional coefficient of the implant-antler interface: experimental approach.

The similar bone structure of reindeer antler to human bone permits studying the osseointegration of dental implants in the jawbone. As the friction is one of the major factors that have a significant influence on the initial stability of immediately loaded dental implants, it is essential to define the frictional coefficient of the implant-antler interface. In this study, the kinetic frictional forces at the implant-antler interface were measured experimentally using an optomechanical setup and a stepping motor controller under different axial loads and sliding velocities.

Clinical and radiographic outcome of dental implants supporting fixed prostheses: the relevance of cortical bone formation.

Purpose: To evaluate the hard and the soft tissue parameters around implants supporting fixed prostheses over a period of 5 years and the possible association to the increase in periimplant bone density (IPBD).

Material And Methods: A total of 39 dental implants placed in 29 patients were included in the study. Periimplant clinical (gingival index, probing depth, keratinized mucosa, sulcus fluid flow rate) and radiographic variables (bone loss, bone density) were collected, and the data analysis performed.

Application and success of two stereolithographic surgical guide systems for implant placement with immediate loading.

Purpose: Two different stereolithographic surgical guide systems, NobelGuide (Nobel Biocare) and SimPlant (Materialise), were compared clinically, and the survival rates of the planned immediately loaded dental implants with prefabricated provisional restorations were evaluated.

Materials And Methods: Patients were treated with implants using either the Materialise SimPlant system or the Nobel Biocare system. All implants were planned on cone beam computed tomography (CBCT) or CT-derived images.

Altered functional activity patterns of fibroblasts related to periodontitis by systemic plasminogen deficiency (ligneous periodontitis).

We report one case of ligneous periodontitis, which is a clinical sign of hypoplasmino-genemia. It appears as massive, painless ulcerated gingival enlargements and alveolar bone destruction in the affected area. The course of the disease is progressive and typically ends with early loss of teeth.

Noninvasive depth profiling of walls by portable nuclear magnetic resonance.

A compact and mobile single-sided (1)H NMR sensor, the NMR-MOUSE, has been employed in the nondestructive characterization of the layer structure of historic walls and wall paintings. Following laboratory tests on a model hidden fresco, paint and mortar layers were studied at Villa Palagione and the Seminario Vescovile di Sant' Andrea in Volterra, Italy. Different paint and mortar layers were identified, and further characterized by portable X-ray fluorescence spectroscopy where accessible.

Development and design of a novel loading device for the investigation of bone adaptation around immediately loaded dental implants using the reindeer antler as implant bed.

The assessment of the behavior of immediately loaded dental implants using biomechanical methods is of particular importance. The primary goal of this investigation is to optimize the function of the implants to serve for immediate loading. Animal experiments on reindeer antlers as a novel animal model will serve for investigation of the bone remodeling processes in the implant bed.

Tactile sensibility of single-tooth implants and natural teeth.

Aim: The purpose of this randomized split-mouth clinical trial was to determine the active tactile sensibility between single-tooth implants and opposing natural teeth and to compare it with the tactile sensibility of pairs of natural teeth on the contralateral side in the same mouth (intraindividual comparison).

Material And Methods: The hypothesis was that the active tactile sensibilities of the implant side and control side are equivalent. Sixty two subjects (n=36 from Bonn, n=26 from Bern) with single-tooth implants (22 anterior and 40 posterior dental implants) were asked to bite on narrow copper foil strips varying in thickness (5-200 microm) and to decide whether or not they were able to identify a foreign body between their teeth.

Incidence and predictive factors for perforation of the maxillary antrum in operations to remove upper wisdom teeth: prospective multicentre study.

Background: Our aim was to evaluate the incidence of perforations of the sinuses and their related treatment after the removal of upper wisdom teeth depending on various anatomical and clinical variables.

Material And Methods: A total of 1057 upper wisdom teeth were removed under local anaesthetic in the departments of oral surgery at the Universities of Bonn, Düsseldorf, Frankfurt and Mainz, Germany. Data were collected with the help of an anonymised questionnaire dealing with information about the patients, and the position and stage of the development of teeth, as well as the occurrence and size of an oro-antral communication and its treatment.