Preserving duodenal passage for bone mineralization: Billroth I versus Billroth II reconstruction after partial gastrectomy in growing minipigs.

Introduction: Recent data in morbid obesity surgery have shown that the Roux-en-Y gastric bypass results in a decrease in bone mass. Therefore, we investigated the impact of duodenal exclusion on bone mineralization in respect to newer duodenal preserving operations in morbid obesity surgery.

Methods: Twelve female minipigs underwent Billroth I (n = 6) or Billroth II (n = 6) reconstruction.

Limited nutritional energy supply differentially impairs growth and bone mineralization of the developing lumbar vertebrae in minipigs.

Bone development during puberty and adolescence may influence the later risk of osteoporosis. The aim of this study was to investigate whether the three-dimensional development of the lumbar vertebrae is impaired in terms of bone mineral density and temporal control during the pubertal growth spurt when caloric intake is limited. Two groups of prepubertal female Gottingen minipigs (each n = 6) were fed either ad libitum (free fed) or with reduced food intake (controlled fed) for 12 months using a standard diet.