Purpose: This article is the first prospective documentation of the efficacy and safety of gamma knife surgery (GKS) in the treatment of drug-resistant epilepsies of mesial temporal lobe origin.
Methods: From July 1996 to March 2000, three European centers selected 21 patients with mesial temporal lobe epilepsy (MTLE) for a temporal lobectomy. The preoperative investigations included video-EEG with foramen ovale electrodes, magnetic resonance imaging, neuropsychological testing, and the ESI-55 quality-of-life questionnaire.
Object: The authors compared the results of gamma knife radiosurgery in patients with uveal melanoma who underwent high-dose (treated from 1992-1995) and low-dose irradiation (treated from 1996-2002).
Methods: Thirty-one patients with uveal melanomas were treated with a mean margin dose of 52.1 Gy (high dose) and 33 with a mean dose of 41.
Objective: To investigate the incidence and clinical findings of radiation retinopathy after single-fraction high-dose gamma knife radiosurgery for choroidal melanoma.
Design: Retrospective noncomparative interventional case series.
Participants: Thirty-two patients with choroidal melanoma.
Although surgeons in Austria, especially in Vienna, were counted among the leading specialists at the end of the 19th century, neurosurgery did not evolve as a distinct discipline before the turn of the century; achievements were episodic until Anton von Eiselsberg became an enthusiastic surgeon of the central nervous system at the beginning of the 20th century. On the threshold of modern microneurosurgery, he was succeeded in Vienna by Leopold Schönbauer and then by Herbert Kraus. Although Schönbauer kept a certain distance from neurosurgery before World War II, a special department of neurosurgery was founded at the University of Graz Medical Faculty in 1950.
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