Publications by authors named "Gergely Kosztyi"
Article Synopsis
- The endoplasmic reticulum (ER) serves as a storage area for calcium (Ca) and is vital for protein processing, which is influenced by the balance between reduced and oxidized forms of glutathione (GSH and GSSG).
- Researchers discovered that decreasing Ca levels in the ER leads to an increase in GSH levels, indicating that GSH plays a key role in the redox state of the ER; this process occurs independently of the calreticulin protein.
- The study suggests that the transport of GSH into the ER, likely involving a GSH transporter that responds to Ca changes, is crucial for maintaining redox balance in the ER, emphasizing its importance in
