Dilution of blood in fresh water drowning. Post-mortem determination of osmolarity and electrolytes in blood, cerebrospinal fluid and vitreous humor.

In an attempt to detect signs of dilution of blood 38 autopsy cases of drowning in fresh water and 35 cases with other causes of death were investigated. Osmolarity and sodium and potassium concentrations were determined in serum from the right and left sides of the heart, cerebrospinal fluiid and vitreous humor..

Protection against the impairment of renal function after intravascular coagulation in the rat kidney by increased ingestion of sodium chloride.

Rats were kept for 4 weeks on a dietary regimen with a low or high sodium intake to increase or reduce, respectively, the renin activity of the kidneys and plasma. Fibrinolysis was inhibited by intravenous injection of AMCA and thrombin was infused into the jugular vein, giving rise to heavy intravascular fibrin deposition in the kidneys. Shortly after the thrombin infusion the glomerular filtration rate (GFR) decreased equally in saline-loaded and normal rats.