The Prolific Ternary System Pt/Sn/Nd: Insertion of Pt into the Structures of Sn/Nd Intermetallics Yields Structural Complexity and Wealth.

The understanding of structure and bonding in intermetallic phases still lags behind that of molecular compounds. For that reason, exploring intermetallic phases and identifying structural patterns and relationships are particularly important for closing this knowledge gap. In particular, here we report on the addition of increasing amounts of platinum to ∼2:1 mixtures of tin and neodymium, which yields eight ternary Pt/Sn/Nd compounds, four of which have not been reported before.

Binary Intermetallics in the 70 atom % R Region of Two R-Pd Systems (R = Tb and Er): Hidden, Obscured, or Nonexistent?

Although rare-earth-metal-transition-metal (R/T) phase diagrams have been explored extensively, our recent studies have uncovered new previously nonexistent binary intermetallics. These compounds belong to a narrow region between 70 and 71.4 atom % of the rare-earth metal but represent four different structure types.

Ternary Polar Intermetallics within the Pt/Sn/R Systems (R = La-Sm): Stannides or Platinides?

Starting generally with a 4:6:3 molar ratio of Pt, Sn, and (where = La-Sm), with or without the application of a NaCl flux, seven ternary compounds were obtained as single crystals. The platinides PtSnR ( = La-Nd) crystallize with the PtGePr type of structure (52, , = 27.6-27.

Adenosine stress perfusion cardiac magnetic resonance imaging in patients undergoing intracoronary bone marrow cell transfer after ST-elevation myocardial infarction: the BOOST-2 perfusion substudy.

Aims: In the placebo-controlled, double-blind BOne marrOw transfer to enhance ST-elevation infarct regeneration (BOOST) 2 trial, intracoronary autologous bone marrow cell (BMC) transfer did not improve recovery of left ventricular ejection fraction (LVEF) at 6 months in patients with ST-elevation myocardial infarction (STEMI) and moderately reduced LVEF. Regional myocardial perfusion as determined by adenosine stress perfusion cardiac magnetic resonance imaging (S-CMR) may be more sensitive than global LVEF in detecting BMC treatment effects. Here, we sought to evaluate (i) the changes of myocardial perfusion in the infarct area over time (ii) the effects of BMC therapy on infarct perfusion, and (iii) the relation of infarct perfusion to LVEF recovery at 6 months.

TbPd, ErPd and ErCo: structural variations and bonding in rare-earth-richer binary intermetallics.

The three binary Tb/Er-rich transition metal compounds TbPd (triterbium dipalladium), ErPd (trierbium dipalladium) and ErCo (hexaerbium pentacobalt) crystallize in the space groups Pbam (Pearson symbol oP20), P4/mbm (tP10) and P6/m (hP22), respectively. Single crystals of TbPd and ErCo suitable for X-ray structure analysis were obtained using rare-earth halides as a flux. TbPd adopts its own structure type, which can be described as a superstructural derivative of the USi type, which is the type adopted by ErPd.

From the Nonexistent Polar Intermetallic PtPr via PtPr to Pt/Sn/Pr Ternaries.

Although the Pt-Pr phase diagram has been explored well, recent work on rare-earth metal cluster halides with endohedral transition metal atoms has provided a new binary intermetallic that is nonexistent in the known phase diagram: The binary PtPr (1) crystallizes in a new structure type ( mP56, P2/ c, a = 12.353(2) Å, b = 7.4837(9) Å, c = 17.

Synthesis and antiproliferative activity of a series of new platinum and palladium diphosphane complexes.

New organometallic complexes [M(dppe)(R)] {where M = Pt or Pd, dppe = 1,2-bis(diphenylphosphano)ethane, and R = CFH-x (x = 6,5,4), CFH-3,5, CFH-5,6, CFH-3,6, CF(OMe)-4, and CF(cyclo-CHN)-4, the numbers x refer to the positions of the protons in the polyfluoroaryl ligands} were synthesised either through transmetalation from the dichlorido complexes [M(dppe)Cl] or through ligand exchange using [M(diene)Cl] precursor complexes with diene = 1,5-cyclooctadiene (cod) or 1,5-hexadiene (hex). Alternatively, [M(dppX)Cl(R)] complexes with dppX = dppm (1,1-bis(diphenylphosphano)methane), dppe, dppp (1,3-bis(diphenylphosphano)propane), and dppb (1,4-bis(diphenylphosphano)butane) were prepared in decarboxylation reactions from thallium(i) carboxylates Tl(OCR). The different preparative methods were compared in terms of yield and purity.

Gold Polar Intermetallics: Structural Versatility through Exclusive Bonding Motifs.

The design of new materials with desired chemical and physical characteristics requires thorough understanding of the underlying composition-structure-property relationships and the experimental possibility of their modification through the controlled involvement of new components. From this point of view, intermetallic phases, a class of compounds formed by two or more metals, present an endless field of combinations that produce several chemical compound classes ranging from simple alloys to true ionic compounds. Polar intermetallics (PICs) belong to the class that is electronically situated in the middle, between Hume-Rothery phases and Zintl compounds and possessing e/a (valence electron per atom) values around 2.

Intracoronary autologous bone marrow cell transfer after myocardial infarction: the BOOST-2 randomised placebo-controlled clinical trial.

Aims: Intracoronary infusion of autologous nucleated bone marrow cells (BMCs) enhanced the recovery of left ventricular ejection fraction (LVEF) after ST-segment elevation myocardial infarction (STEMI) in the randomised-controlled, open-label BOOST trial. We reassessed the therapeutic potential of nucleated BMCs in the randomised placebo-controlled, double-blind BOOST-2 trial conducted in 10 centres in Germany and Norway.

Methods And Results: Using a multiple arm design, we investigated the dose-response relationship and explored whether γ-irradiation which eliminates the clonogenic potential of stem and progenitor cells has an impact on BMC efficacy.

Spontaneous Assembly of an Organic-Inorganic Nucleic Acid Z-DNA Double-Helix Structure.

Herein, we report a hybrid polyoxometalate organic-inorganic compound, Na [(HGMP) Mo O ]⋅7 H O (1; where GMP=guanosine monophosphate), which spontaneously assembles into a structure with dimensions that are strikingly similar to those of the naturally occurring left-handed Z-form of DNA. The helical parameters in the crystal structure of the new compound, such as rise per turn and helical twist per dimer, are nearly identical to this DNA conformation, allowing a close comparison of the two structures. Solution circular dichroism studies show that compound 1 also forms extended secondary structures in solution.

Labile Pd-sulphur and Pt-sulphur bonds in organometallic palladium and platinum complexes [(COD)M(alkyl)(S-ligand)]-A speciation study.

Reaction of various sulphur ligands L (SEt, SPh, SCFH-4, SEt, StBu, SnBu, DMSO, DPSO) with the precursors [(COD)M(R)Cl] (COD=1,5-cyclooctadiene, M=Pd or Pt; R=methyl (Me) or benzyl (Bn); DMSO=dimethyl sulfoxide; DPSO=diphenyl sulfoxide) allowed isolation and characterisation of mononuclear neutral (n=0) or cationic (n=1) complexes [(COD)Pt(R)(L)]. Reaction of l-cysteine (HCys) with [(COD)Pt(Me)Cl] under similar conditions gave the binuclear cationic complex in [{(COD)Pt(Me)}(μ-Cys)]Cl. Detailed NMR spectroscopy and single crystal X-ray diffraction in the case of [(COD)Pt(Me)(SEt)][SbF] and [(COD)Pt(Me)(DMSO)][SbF] reveal markedly labilised Pt-S bonds as a consequence of the highly covalent Pt-C bonds of the R coligands in these organometallic species.

Electron counting rules and electronic structure in tetrameric transition-metal (T)-centered rare-Earth (R) cluster complex halides (X).

Electron partition schemes are a beneficial means to systematize bonding networks and to identify structure-bonding relationships in polar intermetallics. One prolific class of polymetal networks with simple counterions is the broad family of transition-metal (T)-centered rare-earth metal (R) cluster halides (X), which can be isolated or condensed to oligomers and chains. While the electronic structures of R cluster monomers and chains encapsulating T atoms have been studied systematically, the band structures of oligomers, in particular, the most frequent Friauf-type {T(4)R(16)} tetramers, have been investigated to a lesser extent.

Nickel hexa-yttrium deca-iodide, [NiY6]I10.

Comproportionation reactions of yttrium triiodide, yttrium and nickel led to the formation of the compound [NiY6]I10, which is isostructural with the prototypical [RuY6]I10. In particular, [NiY6]I10 is composed of isolated nickel centered yttrium octa-hedra (site symmetry -1) that are further surrounded by iodide ligands to construct a three-dimensional cluster complex framework. Although this compound has been previously detected by powder X-ray diffraction techniques [Payne & Corbett (1990 ▶).

Aerobic training in adults after atrial switch procedure for transposition of the great arteries improves exercise capacity without impairing systemic right ventricular function.

Background: Exercise training safely and efficiently improves symptoms in patients with heart failure due to left ventricular dysfunction. However, studies in congenital heart disease with systemic right ventricle are scarce and results are controversial. In a randomised controlled study we investigated the effect of aerobic exercise training on exercise capacity and systemic right ventricular function in adults with d-transposition of the great arteries after atrial redirection surgery (28.

Theobrominium perchlorate dibenzo-18-crown-6 3.25-hydrate.

The co-crystal, C7H9N4O2 (+)·ClO4 (-)·C20H24O6·3.25H2O, consists of theobrominium (3,7-di-methyl-2,6-dioxo-1H-purin-9-ium) cations, perchlorate anions and dibenzo-18-crown-6 and water mol-ecules. The crown ether is in a bent conformation, in which the planes of the aromatic rings subtend an angle of 63.

Declining cardiopulmonary exercise capacity is not associated with worsening systolic systemic ventricular dysfunction in adults with transposition of great arteries after atrial switch operation.

Background/objective: Cardiopulmonary exercise capacity is often reduced in patients with transposition of the great arteries after atrial switch operation. Reduced exercise capacity may be caused by deterioration of systemic right ventricular function over time. This study analyzed serial changes in systemic right ventricular function and cardiopulmonary exercise capacity in young adults with transposition of the great arteries after atrial redirection surgery.

Clinical features of critically ill patients with Shiga toxin-induced hemolytic uremic syndrome.

Objective: In Spring 2011, an unprecedented outbreak of Shiga toxin-producing Escherichia coli serotype O104:H4-associated hemolytic uremic syndrome occurred in Northern Germany. The aim of this study was to describe the clinical characteristics, treatments, and outcomes of critically ill patients with Shiga toxin-producing E. coli-associated hemolytic uremic syndrome during this outbreak.

Symptoms and clinical course of EHEC O104 infection in hospitalized patients: a prospective single center study.

Objectives: Shiga-toxin producing O157:H7 Entero Haemorrhagic E. coli (STEC/EHEC) is one of the most common causes of Haemolytic Uraemic Syndrome (HUS) related to infectious haemorrhagic colitis. Nearly all recommendations on clinical management of EHEC infections refer to this strain.

Dihydro-nium tetra-chromate(VI), (H(3)O)(2)Cr(4)O(13).

The crystal structure of (H(3)O)(2)Cr(4)O(13) is isotypic with K(2)Cr(4)O(13). The finite tetra-chromate anion in the title structure consists of four vertex-sharing CrO(4) tetra-hedra and exhibits a typical zigzag arrangement. The crystal packing is stabilized by hydrogen bonds between these anions and hydro-nium cations.

Identifying a structural preference in reduced rare-earth metal halides by combining experimental and computational techniques.

The structures of two new cubic {TnLa(3)}Br(3) (Tn = Ru, Ir; I4(1)32, Z = 8; Tn = Ru: a = 12.1247(16) Å, V = 1782.4(4) Å(3); Tn = Ir: a = 12.

Tetra-μ-acetato-bis-[(1,3-benzothia-zole)copper(II)](Cu-Cu).

The title compound, [Cu(2)(CH(3)CO(2))(4)(C(7)H(5)NS)(2)] or [(C(7)H(5)NS)Cu](2)(μ-O(2)CCH(3))(4), crystallizes with one mol-ecule per unit cell. The coordination number of copper is six with four basal O atoms, one axial N atom and one axial Cu atom. Four acetate ligands act as bidentate linker and connect two Cu atoms, with a crystallographic inversion center located at the mid-point of the Cu-Cu bond.

Anomalous intramural course of coronary arteries in congenital heart disease--three case reports and review of the literature.

Anomalies of the coronary arteries are commonly associated with congenital heart disease (CHD). Anomalies include variations in number, shape, and location of the origin, as well as the course of the coronary artery. An intramural course of one of the coronary arteries is a rather rare condition.