Publications by authors named "Gerardo Rodriguez-Martinez"
Introduction: The impact of acute severe hepatitis of unknown origin in children (SHIC) subject to a medical alert in 2022 medical alert is poorly understood.
Materials And Methods: Observational study of the incidence, aetiology and clinical presentation of acute hypertransaminasaemia (HTRA) with laboratory values in the severe range (ALT and/or AST ≥ 500 U/L) in paediatric patients (age 0 to 16 years) in one health care zone from 2012 to 2022, comparing the periods of the SHIC alert and the SARS-CoV2 pandemic with previous years.
Results: The incidence of severe HTRA of any cause was 195.
Aim: Maternal health and gestational control are crucial to improving the newborn's prognosis. This study analyses demographic and obstetric factors at the beginning of pregnancy related to neonatal health, assessing their impact on the risk of hospital admission and prematurity.
Methods: Observational retrospective study conducted in Northeast Spain with data of 9560 newborns between February 2017 and February 2022.
Rapid Growth between 0 and 2 Years Old in Healthy Infants Born at Term and Its Relationship with Later Obesity: A Systematic Review and Meta-Analysis of Evidence.
Nutrients
September 2024
Introduction: Rapid growth in early childhood has been identified as a possible risk factor for long-term adiposity. However, there is a lack of studies quantifying this phenomenon only in healthy, full-term infants with appropriate birth weight for gestational age. This systematic review and meta-analysis aimed to investigate the association of rapid growth in full-term children up to 2 years of age with adiposity up to 18 years of age.
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- * A retrospective study analyzed data from 2008 to 2022, involving 104 diagnosed patients, revealing an increasing annual incidence rate among children.
- * The incidence rose from 1.2 cases per 100,000 in 2008-2012 to 8.1 cases per 100,000 in 2018-2022, indicating a seven-fold increase in risk for later diagnosed patients.
Introduction: There are various scales designed to determine the risk of malnutrition at hospital admission in children. However, most of these instruments are developed and published in English. Their cross-cultural adaptation and validation being mandatory in order to be used in our country.
View Article and Find Full Text PDFBackground: Studies on childhood obesity mainly focus on the genetic component and on the lifestyle that may be associated with the development of obesity. However, the study of perinatal factors in their programming effect toward future obesity in children or adults is somewhat more recent, and there are still mechanisms to be disentangled.
Summary: In this narrative review, a comprehensive route based on the influence of some early factors in life in the contribution to later obesity development is presented.
Article Synopsis
- Changes in liver function tests, like ALT levels, can be non-specific but may indicate serious underlying diseases, particularly in asymptomatic patients.* -
- In a study of 572 blood tests, 305 patients were assessed after excluding those with prior liver issues; only 22.6% were diagnosed with a condition explaining their ALT elevation, and follow-up was inadequate for most.* -
- The findings highlight that many children with unexplained high ALT levels are not properly monitored, suggesting a significant opportunity for diagnosing and treating potential liver diseases is being overlooked.*
Most of the studies analyzing the effect of moderate to vigorous physical activity (MVPA) on children's health do not contain information on early stages or do not use accurate methods. We investigated the association between PA and body composition using objective methods, perinatal data, lifestyle behaviors, and World Health Organization (WHO) physical activity (PA) recommendations. The CALINA study is a longitudinal observational cohort study of children born in Aragon (Spain) in 2009.
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- Patients with moderate-severe cerebral palsy often rely heavily on caregivers for daily activities due to their motor impairments and associated comorbidities.
- The study examined 69 children with cerebral palsy, analyzing the relationship between their motor function levels, nutritional status, and the challenges faced by caregivers in supporting daily living tasks.
- Findings revealed that caregiver burden is significantly influenced by the severity of the child's motor function and nutritional status, indicating that addressing these factors could help reduce difficulties in caregiving.
Article Synopsis
- Bone health in pediatric patients with cerebral palsy (CP) is often poor due to nutritional deficits, which can lead to low bone mineral density and an increased risk of asymptomatic vertebral fractures.
- The study involved 51 children aged 11, focusing on their bone density and assessing factors like nutritional status and neurological function using various measurements.
- Results indicated that over half of the children had low bone density, with a notable prevalence of vertebral fractures, particularly in those with more severe neurological impairments.
Physical activity (PA) and exercise improve the overall quality of life, as well as prevent the onset of diseases in healthy children and adolescents, and as an aid to treat prevalent chronic diseases in childhood. PA and exercise are like medicine, but sedentary lifestyle and inactivity cause disease. In this article, the existing scientific evidence in this field is reviewed and recommendations for professionals involved in child health are updated.
View Article and Find Full Text PDFPregnancy induces a number of immunological, hormonal, and metabolic changes that are necessary for the mother to adapt her body to this new physiological situation. The microbiome of the mother, the placenta and the fetus influence the fetus growth and undoubtedly plays a major role in the adequate development of the newborn infant. Hence, the microbiome modulates the inflammatory mechanisms related to physiological and pathological processes that are involved in the perinatal progress through different mechanisms.
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- - Cerebral palsy (CP) is a major cause of motor disability in children, and this study investigates the nutritional status of CP patients aged 4-15 years, looking at how it relates to their neurological condition.
- - The research involved 69 patients from a specialized pediatric hospital, assessing their nutritional habits, body composition, and motor function using metrics like the Gross Motor Function Classification System (GMFCS).
- - Findings revealed a significant number of patients with malnutrition, especially in those with higher GMFCS grades, alongside a notable prevalence of overweight/obesity, indicating a complex relationship between motor function and nutritional status.
Background: the main action of vitamin D is to maintain the concentration of calcium and phosphorus within the physiological range, allowing normal metabolism and bone mineralization. Vitamin D receptors have recently been described in many tissues, therefore vitamin D deficiency has been related not only to rickets, but also to increased risk of diabetes, obesity, cardiovascular, oncological, infectious and autoimmune diseases.
Objective: the aim of the study was to know the vitamin D concentration in a healthy pediatric population and to verify its influential factors, as well as to analyze the current situation of vitamin D prophylaxis and to evaluate the effectiveness of current recommendations.
Article Synopsis
- - The low FODMAP diet, typically effective for adults with irritable bowel syndrome, was assessed for its impact on children with functional abdominal pain in a Mediterranean area, showing promising results.
- - In a study involving 22 participants, data collected before and after a two-week low FODMAP diet indicated significant reductions in abdominal pain episodes, pain severity, and gastrointestinal symptoms.
- - The diet was well-received by the children, with only 15% reporting difficulty in adherence, suggesting that the low FODMAP diet can be successfully implemented in young patients for managing abdominal pain.
Background: Significant efforts have been made to improve the nutritional support of very preterm infants. Large surveys may help to know the nutritional practices for preterm infants in neonatal units and identify if they are in line with the current guidelines.
Methods: A multicentre nationwide web-based survey on clinical feeding practices in very low birth weight (VLBW) infants was conducted in tertiary neonatal hospitals that admit infants with a birth weight < 1,500 g and/or a gestational age of < 32 weeks.
Article Synopsis
- The study aimed to evaluate how reliable two nutritional screening tools (STRONGkids and STAMP) are in identifying malnutrition risk in children admitted to hospitals, through observations by both nutrition experts and nonexperts.
- Involving 223 pediatric patients, the results showed good agreement between expert and nonexpert staff, with both groups identifying similar proportions of high-risk patients using the tools.
- The findings suggest that STRONGkids and STAMP can effectively guide nutritional screening regardless of the observer's expertise, with higher risk scores correlating with longer hospital stays.
Objective: To check whether secular changes exist in growth pattern of caucasic children from the North of Spain up to 2 years of age compared with 25-30 years ago population growth curves.
Material And Methods: Longitudinal study of a representative cohort of caucasic infants born a term in Aragon (n=1.099).