Rhododendrons ( spp.) are ornamental plants in the family Ericaceae that thrive in acidic soils and are challenged by neutral or alkaline soils. This soil requirement limits the locations where rhododendrons can be grown and causes chlorosis, diminished growth, and low survival when rhododendrons are grown in high pH soils.
View Article and Find Full Text PDFNicotinic acetylcholine receptors (nAChRs) modulate synaptic activity in the central nervous system. The α7 subtype, in particular, has attracted considerable interest in drug discovery as a target for several conditions, including Alzheimer's disease and schizophrenia. Identifying agonist-induced structural changes underlying nAChR activation is fundamentally important for understanding biological function and rational drug design.
View Article and Find Full Text PDFBackground: The usual analysis of RNA sequencing (RNA-seq) reads is based on an existing reference genome and annotated gene models. However, when a reference for the sequenced species is not available, alternatives include using a reference genome from a related species or reconstructing transcript sequences with de novo assembly. In addition, researchers are faced with many options for RNA-seq data processing and limited information on how their decisions will impact the final outcome.
View Article and Find Full Text PDFBackground: Blueberries are one of the few horticultural crops adapted to grow in acidic soils. Neutral to basic soil pH is detrimental to all commonly cultivated blueberry species, including Vaccinium corymbosum (VC). In contrast, the wild species V.
View Article and Find Full Text PDF