Mechanistic characterization and inhibition of sphingomyelinase C over substituted Iron Schiff bases of chitosan adsorbed on glassy carbon electrode.

The medical treatment of laxoscelisms is based solely on supportive measures. Although equine antiserum for Sphingomyelinase C (SMASE) and D isomers are available, it is not used due to the risk of an anaphylactic reaction and its unproven efficacy. As potential enzyme inhibitors, derivatives of Iron chitosan complexes were studied (Shiff base having -R = -H, -Cl, -Br, -F, -OCH, -CH, -NO).

Antibacterial activity of an oligosaccharide of native Paecilomyces sp. and its aminoglycosylated derivative.

This study reports the antibacterial activity of an oligosaccharide, prepared by partial acid hydrolysis of a native Paecilomyces sp. exopolysaccharide, and of its aminoglycosylated derivative, prepared by reductive alkylation of the oligosaccharide, against E. coli and S.

Antibacterial activity of chitooligosaccharides.

The aim of this study was to investigate the antibacterial activity of chitooligosaccharide, prepared by partial acid hydrolysis of chitosan, and of an aminoglycosylated derivative, prepared by reductive alkylation of the chitooligosaccharide, against E. coli and S. aureus.

Structural studies of native Paecilomyces sp. Exopolysaccharide.

A polysaccharide separated from Paecilomyces sp. was determined by gel permeation chromatography to be homogeneous. HPLC showed a monosaccharide containing D-glucose and D-fructose at a ratio of about 2:1.

Production of exopolysaccharides by a submerged culture of an entomopathogenic fungus, Paecilomyces sp.

Exopolysaccharide basic was obtained from a submerged culture of a native Paecilomyces sp. strain isolated from Chilean soil.