PP077. New prognostic marker for the risk to develop early-onset preeclampsia.

Introduction: ESM-1 plays a role in the regulation of angiogenesis and is released by activated endothelial cells.

Objective: To test the hypothesized that ESM-1 is increased in preeclampsia (PE).

Methods: Plasma samples from high risk pregnancies divided in 23 healthy (CON), 11 severe early-onset PE (SE) and 7 severe late-onset PE (SL) pregnancies were collected at regular intervals between week 12 and birth.