Drug release from hydroxypropylcellulose gels cannot be statistically predicted from their viscometric and initial viscoelastic properties.

This study questioned whether rheological properties can predict drug (metronidazole) release from Hydroxypropylcellulose (HPC) platforms. Viscometric and viscoelastic properties of aqueous, alcohols/diols and mixed solvent HPC solutions and gels were determined using viscometry and oscillatory analysis. Drug release was conducted at pH 7.

The hepatobiliary complications of malnutrition and nutritional support in adults.

Hepatobiliary complications of hypoalimentation and parenteral nutrition (PN) are widely recognised. Hypoalimentation includes conditions such as anorexia nervosa (AN), obesity malnutrition and liver disease following bariatric surgery. Treatment of the underlying condition causing hypoalimentation can result in an improvement in liver dysfunction.

Design of binary polymeric platforms containing ɩ-carrageenan and hydroxypropylcellulose for use in cataract surgery.

This study describes the design and characterisation of the rheological and mechanical properties of binary polymeric systems composed of 2-Hydroxypropylcellulose and ɩ-carrageenan, designed as ophthalmic viscoelastic devices (OVDs). Platforms were characterised using dilute solution, flow and oscillatory rheometry and texture profile analysis. Rheological synergy between the two polymers was observed both in the dilute and gel states.

Endoscopic placement of enteral feeding tubes.

Malnutrition is common in patients with acute and chronic illness. Nutritional management of these malnourished patients is an essential part of healthcare. Enteral feeding is one component of nutritional support.