Publications by authors named "Gerard Bijaoui"

Study Question: Are anti-Müllerian hormone (AMH) levels lower in women with endometriosis, notably those with endometriomas (OMAs) and deep infiltrating lesions, compared with controls without endometriosis?

Summary Answer: Endometriosis and OMAs per se do not result in lower AMH levels. AMH levels are decreased in women with previous OMA surgery independently of the presence of current OMAs.

What Is Known Already: The impact of endometriosis and OMAs per se on the ovarian reserve is controversial.

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Article Synopsis
  • The study investigates the relationship between oral contraception (OC) use and different types of endometriosis, analyzing data from over 1,000 women, including both controls and those with diagnosed endometriosis.
  • Results indicate that women who have previously used OC, particularly for severe primary dysmenorrhea, show a higher incidence of endometriosis, especially deep infiltrating endometriosis (DIE).
  • However, current OC users do not have an increased prevalence of endometriosis, suggesting that while past OC use may be linked to later diagnosis, it does not directly increase the risk of developing endometriosis.
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Smoking habits did not influence either the risk of any form of endometriosis (superficial peritoneal endometriosis, ovarian endometriomas, and deep infiltrating endometriosis) and did not correlate with the revised American Fertility Society stages or scores.

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Background: Matrix metalloproteinases (MMPs) may contribute to endometriosis. We tested whether eight functional polymorphisms of these genes could modify the risk of endometriosis.

Methods: In this case-control study, 227 endometriosis and 241 controls were genotyped for MMP1 -1607 1G/2G, MMP2 -1575 G/A (MMP2.

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Objective: To investigate whether the controversy about fluctuations of anti-Müllerian hormone (AMH) levels during the menstrual cycle results from differences between the immunoassays currently available: the Beckman Coulter Immunotech kit (Fullerton, CA) and the Diagnostic Systems Laboratories kit (Webster, TX).

Design: Prospective trial.

Setting: Fertility clinics of two tertiary university hospitals.

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Detection and quantification of Mycoplasma genitalium were evaluated in 83 patients with urethritis (group 1), 60 patients with urethral symptoms but no urethritis (group 2), and 50 asymptomatic men (group 3). Quantification of M. genitalium was carried out using real-time polymerase chain reaction (PCR) analysis of first-pass urine samples.

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