Acute and Repeated Dose 28-Day Oral Toxicity Study of the Aqueous Extracts from the Leafy Stem and Fruit of D.Royen EX.L in Wistar Rats.

Background: () is used in folk medicine for treatment of male infertility. However, scientific data on its safety are limited.

Objective: This study was carried out to assess the acute and repeated dose 28-day oral toxicity of the aqueous extracts from leafy stem and fruit in Wistar rats.

Aqueous extract of D. Royen ex L leafy stem protects against lead induced testicular toxicity in Wistar rats.

Objectives: Lead exposure seriously impairs male reproductive function. The protective capacity of leafy stem and fruit aqueous extracts against lead testicular toxicity is evaluated to find herbals drugs able to improve semen quality.

Methods: Phytochemical screening were performed according to classical methods.