Relationship between Daytime Sleepiness and Intrinsically Photosensitive Retinal Ganglion Cells in Glaucomatous Disease.

Patients with glaucoma showed to have higher daytime sleepiness measured by Epworth sleepiness scale. In addition, this symptom was associated with pupillary reflex and polysomnography parameters. These ipRGC functions might be impaired in patients with glaucoma, leading to worse quality of life.

Intrinsically photosensitive retinal ganglion cell activity is associated with decreased sleep quality in patients with glaucoma.

Purpose: To use the pupillary light reflex and polysomnography to evaluate the function of intrinsically photosensitive retinal ganglion cells (ipRGCs) and to correlate this function with structural damage in glaucoma.

Design: Cross-sectional study.

Participants: A study was conducted on both eyes of 45 participants (32 patients with glaucoma and 13 healthy subjects).

Severe acute pancreatitis: results of treatment.

Objective: To evaluate the results of the Protocol for treatment of patients with severe acute pancreatitis.

Methods: We consecutively analyzed age, gender, etiology, length of hospital stay, type of treatment and mortality of 37 patients with severe acute pancreatitis from January 2002.

Results: The patients' ages ranged from 20 to 88 years (average 50 years), 27% were female and 73% male.