Adverse reactions of low osmolar non-ionic and ionic contrast media when used together or separately during percutaneous coronary intervention.

Background: Due to perceived advantages in the use of non-ionic contrast agents for diagnostic angiography and ionic agents for percutaneous coronary intervention (PCI), patients often receive various combinations of both types of agents.

Aim: To assess potential adverse effects of non-ionic and ionic contrast media when used together or separately during percutaneous coronary intervention.

Methods: We retrospectively evaluated the outcomes of 532 patients undergoing percutaneous coronary intervention in our institution.