Publications by authors named "Gerald Lirk"

Background: Dietary inorganic nitrate (NO) and its reduced forms nitrite (NO) and nitric oxide (NO), respectively, are of critical importance for host defense in the oral cavity. High concentrations of salivary nitrate are linked to a lower prevalence of caries due to growth inhibition of cariogenic bacteria.

Objective: In-vitro studies suggest that the formation of antimicrobial NO results in an increase of the pH preventing erosion of tooth enamel.

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Article Synopsis
  • The text discusses various research studies focusing on health topics, including health literacy in adolescents and the impact of walking programs on individuals with schizophrenia.
  • It also covers innovative medical practices, safety culture in patient care, and the psychological effects experienced by emergency crews after disasters.
  • Additionally, it highlights issues such as musculoskeletal disorders in midwives, negative childhood experiences affecting adolescent mental health, and studies on vaccination timing and assessments in elderly care.
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Background: Metabolomics experiments often comprise large numbers of biological samples resulting in huge amounts of data. This data needs to be inspected for plausibility before data evaluation to detect putative sources of error e.g.

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Motivation: Liquid chromatography-mass spectrometry (LC/MS) is a key technique in metabolomics. Since the efficient assignment of MS signals to true biological metabolites becomes feasible in combination with in vivo stable isotopic labelling, our aim was to provide a new software tool for this purpose.

Results: An algorithm and a program (MetExtract) have been developed to search for metabolites in in vivo labelled biological samples.

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