Publications by authors named "Geraghty T"

Objectives: To determine rates of opioid and concomitant antidepressant, anticonvulsant and benzodiazepine dispensing in the post-discharge period, after acute spinal cord injury (SCI).

Design: Single-center prospective cohort study with 12-month linked pharmaceutical data.

Setting: Community pharmaceutical dispensing.

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Risk assessments are important tools to identify deficits in biosecurity management practices. A major strength of some existing tools is that they facilitate cross-country comparisons. However, a weakness is their failure to account for unique intra-national farming enterprise structures such as, for example, pasture-based dairying.

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Background: Osteoarthritis (OA) is a painful degenerative joint disease and a leading source of years lived with disability globally due to inadequate treatment options. Neuroimmune interactions reportedly contribute to OA pain pathogenesis. Notably, in rodents, macrophages in the DRG are associated with onset of persistent OA pain.

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Article Synopsis
  • - This study investigates Mycoplasma bovis (M. bovis) infection in cattle, which can cause various health issues, aiming to analyze the genetic diversity of M. bovis strains from clinical samples in Ireland and Scotland.
  • - Researchers sequenced the genomes of 24 M. bovis strains (19 from Ireland and 5 from Scotland) and compared them to 117 existing genetic assemblies to create a phylogenetic tree, identifying Irish strains in two groups and all Scottish strains in one.
  • - The findings highlight the similarities between Irish and Scottish M. bovis strains and underscore the importance of biosecurity in cattle management due to the global spread of this infection facilitated by international cattle movement.
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Background: Children and young people (CYP) seen by child and adolescent mental health services (CAMHS) often experience safeguarding issues. Yet little is known about the volume and nature of these risks, including how different adversities or risks relate to one another. This exploratory study aims to bridge this gap, examining rates at entry to services and profiles of risk using a latent class analysis.

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  • Osteoarthritis (OA) is a painful joint disease related to neuroimmune interactions, with macrophages in the dorsal root ganglia (DRG) contributing to OA pain in animal models.
  • In experiments, researchers depleted certain macrophages in male and female mice using a specific drug to assess changes in pain behaviors and joint damage following two types of joint surgeries.
  • Results showed that macrophage depletion reduced pain symptoms in both male and female mice but did not affect cartilage damage or inflammation levels, while specific types of macrophages in the DRG were significantly decreased after treatment.
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  • Adults with spinal cord injury (SCI) aged 45 and older often engage in low levels of leisure-time physical activity (LTPA), which can increase their risk of health issues.
  • In a study of 1,281 participants, nearly 44% reported no engagement in LTPA, with an average participation of about 197 minutes per week, with notable differences based on gender and type of injury.
  • The findings suggest a need for targeted initiatives to promote physical activity, particularly focusing on women and those with non-traumatic injuries in this age group.
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Study Design: Cross-sectional survey.

Objectives: Appropriate and timely lifelong access to healthcare following a spinal cord injury (SCI) is critical, yet unmet healthcare needs in this population are common. Poor experiences with healthcare providers can be a barrier to health-seeking behaviour, and we hypothesised that there would be an association between unmet healthcare needs and care experiences.

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Objective: To investigate the relationship between preinjury or early personal resources and long-term psychosocial outcomes following moderate-to-severe traumatic brain injury (TBI) and examine evidence for the stability of personal resources over time.

Methods: The review protocol was registered with the International Register of Systematic Reviews (PROSPERO, Registration No. CRD4202341056).

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Objective: To determine the prevalence, reported harms and factors associated with opioid use among adults with spinal cord injury (SCI) living in the community.

Study Design: Systematic review and meta-analysis.

Methods: Comprehensive literature searches were conducted in PubMed (MEDLINE), EMBASE, CINAHL, Web of Science and Scopus for articles published between 2000 and 2023.

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Study Design: Cross-sectional study.

Objectives: Work-related disability is common in persons with spinal cord injury (SCI). The aims of this study are to examine the associations of employment with self-perceived health (SPH) and quality of life (QoL) across 22 countries and to explore the covariates around employment and SPH and QoL.

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The welfare and economic impact of bovine respiratory disease complex (BRDC), and its associated antibiotic usage, are major challenges to cattle rearing and beef cattle finishing industries. Accurate pathogen diagnosis is important to undertake appropriate treatment and long-term management strategies, such as vaccine selection. Conventional diagnostic approaches have several limitations including high costs, long turnaround times and difficulty in test interpretation, which could delay treatment decisions and lead to unnecessary animal losses.

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Article Synopsis
  • - The study investigates different experiences and hidden disabilities among people with spinal cord injuries (SCI), using data from a survey of 1579 Australian participants.
  • - Results show that lower functional independence can sometimes coincide with high quality of life and mental health, and many ambulant individuals face significant hidden impairments similar to those using wheelchairs.
  • - The conclusion emphasizes the importance of continuous support and access to specialized rehabilitation services for all SCI individuals, regardless of their injury severity or independence level, to better identify and address hidden disabilities.
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Background: Return-to-work (RTW) is often viewed as an important outcome following acquired brain injury (ABI) and spinal cord injury (SCI), although not all individuals have vocational goals and many experience barriers to RTW.

Objective: This study investigated the relationship between RTW and psychosocial functioning at 12-months post-discharge after ABI and SCI and examined patterns of RTW according to perceived need for and receipt of vocational support.

Methods: A file audit was conducted for 69 participants with ABI (n = 44) and SCI (n = 25).

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Introduction: Doctors working in rehabilitation settings have specialized clinical skills and experience, but research activity may be constrained by time pressures and inadequate current skills. This means missed opportunities to contribute to the evidence-base for better clinical practice and outcomes for people living with disabling, chronic complex conditions. This research aimed to understand rehabilitation doctors' research needs, experience, and aspirations to enable future training initiatives that are tailored to their practice context.

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Purpose: This study aimed to compare stigma levels after acquired brain injury (ABI) and spinal cord injury (SCI) during the first 12-months post-discharge and investigate relationships between stigma, psychological distress and community integration.

Methods: 110 adults with ABI (55%) or SCI (45%) were recruited from brain and spinal cord injury inpatient rehabilitation units of a tertiary healthcare facility. They were administered Neuro-QOL Stigma subscale and Depression Anxiety and Stress Scales (DASS-21) at discharge, 3-months and 12-months post-discharge, and Community Integration Measure at 12-months post-discharge.

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Article Synopsis
  • Osteoarthritis (OA) pain management is currently inadequate, particularly as aging is the strongest predictor for its development; this study aims to explore age-related changes in OA and pain mechanisms using a mouse model.
  • Male mice at 20 months showed more severe cartilage degeneration and increased pain responses compared to younger mice, while older female mice had some degeneration but were less affected; this indicates age impacts OA severity differently by sex.
  • Immune cell analysis in the dorsal root ganglion (DRG) of older mice showed significant changes, such as increased macrophages, which could open new pathways for developing treatments for OA.
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Purpose: This scoping review examined the methodologies used to measure access to care in serious injury-related disability populations, for whom access to care post-discharge has significant implications for patient outcomes and rehabilitation trajectories.

Methods: Four electronic databases were searched for literature published between 1 January 2000 and 15 February 2022. Relevant articles needed to relate to access to care in adult community-dwelling trauma and rehabilitation populations.

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This study described leisure-time physical activity (LTPA) for people in Australia with spinal cord injury (SCI) and whether certain sociodemographic and psychosocial variables might be associated with LTPA uptake and guidelines adherence. The Physical Activity Scale for Individuals with a Physical Disability was used to measure the intensity and volume of LTPA of 1,579 individuals with SCI. Summary statistics were calculated for LTPA guidelines adherence.

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Objectives This study explored publicly funded health system and patient expenditure in the post-acute phase following discharge from inpatient acquired brain injury (ABI) or spinal cord injury (SCI) rehabilitation. The secondary aim was to explore sociodemographic and injury characteristics associated with high costs. Methods This was a prospective cohort study.

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Heifer mastitis in early lactation impacts negatively on animal welfare, milk production and longevity. A major challenge for the prevention and control of mastitis in dairy heifers is to establish when intramammary infection occurs because pre-partum secretum sampling is risky. We evaluated a ventrodorsal projection to capture thermal images of the entire udder of primigravid and compared results against caudocranial projection, which is used in lactating cattle.

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Background: Data informing energy needs of people with spinal cord injury (SCI) and pressure injuries are scarce, the impact of surgical repair unknown, and the role of body composition in healing unexplored. The study aims were to investigate resting energy expenditure (REE) over the course of pressure injury surgical repair, compare with available energy prediction equations, and explore associations between body composition and wound healing.

Methods: Indirect calorimetry measured REE pre-surgery, post-surgery, at suture removal and hospital discharge.

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Study Design: Cross-sectional survey.

Objectives: To describe design and methods of Australian arm of International Spinal Cord Injury (Aus-InSCI) community survey, reporting on participation rates, potential non-response bias and cohort characteristics.

Setting: Survey of community-dwelling people with SCI at least 12 months post-injury, recruited between March 2018 and January 2019, from state-wide SCI services, a government insurance agency and not-for-profit consumer organisations across four Australian states.

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Diabetic glomerular injury is a major complication of diabetes mellitus and is the leading cause of end stage renal disease (ESRD). Healthy podocytes are essential for glomerular function and health. Injury or loss of these cells results in increased proteinuria and kidney dysfunction and is a common finding in various glomerulopathies.

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This study described access potential in South-East Queensland, to healthcare services commonly used by people with acquired disability; and investigated the association between service proximity and perceived service obstacles. First, we described accessibility by conducting a spatial analysis to create maps of potential accessibility to health services in South-East Queensland. Queensland statistical area level 2 (SA2) locations were combined with the residential locations of participants from a longitudinal cohort study involving people with ABI and SCI.

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