Publications by authors named "Gepner-Wozniewska M"

Among Poles emigrating from Poland in XIX century (after November and January insurrection) there have been physicians and students of medicine - practising in insurgent troops - and young people, who after arrival in France started medical studies at the medical faculties of Paris, Montpellier, and Strasburg. In Strasburg between 1833 and 1870 there have been promoted 1440 doctors of medicine, including 15 Polish emigrants (three have been granted diplomas before coming to France) and two sons of emigrants. Generally all of them were subsidized by the French government and released from additional payments.

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Low dose Ara-C (10-15 mg/m2) was administered subcutaneously in 1-5 courses of 14 to 21 days to 16 patients with acute nonlymphoblastic leukaemia, mostly in elderly persons and/or with pancytopenia in whom conventional chemotherapy was contraindicated or ineffective. 18 of the 26 patients were females and 8 males. The mean age was 54.

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On the basis of standardized protocols of the therapeutic results of acute non-lymphoblastic leukaemias in adults sent to the Institute of Haematology in Warsaw from 8 haematological centres in Poland it was demonstrated that complete remission occurred in 34.4% of patients (129 out of 375 cases). The mean survival time of the patients treated intensively according to programmes I, II, III and IV 8.

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Thirty patients with acute non-lymphoblastic leukaemia were treated. They were randomly assigned to treatment according to programme AR (14 patients) and RAMP (16 patients). The groups were comparable for age and haematological state.

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Out of 49 adult patients with acute leukaemia admitted successively over a period of 3 years (1976-1978) those surviving next 1.5 year were followed up (till June 30 1980). Forty-one cases were qualified for combined treatment with cytostatic drugs.

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In a period of 5 years 106 patients with acute leukemia were treated (93 with acute nonlymphoblastic leukemia and 13 with acute lymphoblastic leukaemia. Four therapeutic programmes were used. Complete remission (CR) was achieved in 41% of patients, including 37% of those with acute non-lymphoblastic leukaemia and 77% with acute lymphoblastic leukaemia.

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In 100 patients with various haematological syndromes and in 22 healthy subjects serum transferrin was determined by the method of radial immunodiffusion of Mancini. The results were correlated with total iron-binding capacity, iron concentration, beta1 globulin and albumin levels. A statistically significant rise in serum transferrin concentration was demonstrated only in patients with sideropenic anaemia.

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The author observed a 20-year-old patient with selective aplasia of the erythrocytopoietic system developing during virus hepatitis and disappearing completely after one year.

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The authors analysed 202 cases of chronic lymphatic leukaemia comparing the course of this disease in patients above and below 60 years of age. The observation included patients with various forms of this disease--with morphological and clinical findings compatible with mild disease and cases with severe course with complications. It was observed that in severe form of lymphatic leukaemia the course of the disease is similar in both groups of patients and the shorter survival of patients in the older group is frequently due to coexistence of other diseases impairing the general condition and changes connected age.

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