Publications by authors named "Geovanna Peter Correa"
Front Hum Neurosci
February 2024
Article Synopsis
- MicroRNAs (miRNAs), such as hsa-miR-423-5p, play a significant role in regulating gene expression and are important for various biological processes, especially during pregnancy when maternal health impacts infant development.
- A longitudinal study conducted in southern Brazil examined the relationship between maternal levels of hsa-miR-423-5p in early pregnancy and cognitive development in infants at 90 days old, using blood samples and cognitive assessments.
- Results showed that higher maternal levels of miR-423-5p correlate with better cognitive abilities in infants, suggesting this miRNA could serve as a prenatal biomarker for predicting and potentially improving child neurocognitive development through early interventions.
Article Synopsis
- The study investigates the T102C polymorphism of the 5HT2A receptor's relation to oral dysplasia in potentially malignant lesions, looking specifically at the effects of smoking and alcohol consumption.
- It involved a case-control design with 110 participants, revealing significant differences in genotype and allele frequencies between dysplastic patients and healthy controls, suggesting a higher risk of dysplasia linked to the T allele.
- The findings indicate that while the T102C polymorphism increases the risk for oral dysplasia, no significant connection was found between smoking and alcohol habits with dysplasia prevalence in this context.
