Publications by authors named "Georgy Gudkov"
We have studied the formation of a resistive region in the capillary during DNA separation. This effect is caused by an unequal change in the mobilities of cations and anions at the interface between the running buffer solution and the capillary. We studied the motion of the resistive region boundary by sequential removal of portions of the affected capillary end.
View Article and Find Full Text PDFArticle Synopsis
- Developed high-performance capillary DNA sequencing instruments using a new multicolor fluorescent detection technology.
- The technology features multilaser excitation for fluorescence and "color-blind" single-photon detection for better accuracy.
- Discussed design, testing results of single lane sequencers, and plans for scaling to multilane models.