Publications by authors named "Georgios Tsagalis"

Article Synopsis
  • The study investigates the link between the rate of blood pressure (BP) variation and the severity of coronary artery lesions in normotensive patients suspected of having coronary artery disease.
  • Findings indicate that patients with coronary artery disease showed higher daytime rates of systolic BP variation compared to controls, and this variation is independently associated with the severity of coronary lesions as measured by the Gensini score.
  • The research suggests that greater BP variability may stress arterial walls more significantly, potentially being an important factor in assessing coronary artery disease risk alongside traditional factors like diabetes and smoking.
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Background: Recent studies have reported that prehypertension is associated with increased values of common carotid artery intima-media thickness (CCA-IMT). The aim of this study was to assess the impact of daytime ambulatory blood pressure (BP) levels on the association of prehypertension with CCA intima-media thickening in prehypertensive subjects.

Methods: A total of 807 subjects with office systolic BP<140 and diastolic BP<90mmHg, underwent 24h ambulatory BP (ABP) monitoring and carotid artery ultrasonographic measurements.

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Article Synopsis
  • The study investigated the link between blood pressure (BP) variation and renal function in untreated hypertensive patients using 24-hour ambulatory BP monitoring.
  • A total of 803 patients were classified based on their estimated glomerular filtration rate (eGFR), with those having lower eGFR showing significantly higher rates of systolic BP variation.
  • Results indicate that the 24-hour rate of systolic BP variation is a significant independent factor associated with impaired renal function, suggesting that BP fluctuations should be considered alongside traditional BP measurements when evaluating target-organ damage in hypertensive patients.
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