Δ-THC and CBD in Plasma, Oral Fluid, Exhaled Breath, and Urine from 23 Patients Administered Sativex.

Detecting the presence of Δ-THC and CBD is mainly done through venous blood sampling, but other methods are becoming available. Oromucosal administration of Δ-THC and CBD is less studied than inhalation, but this mode of administration is growing. In this study, we analyze samples obtained through invasive and noninvasive methods in a cohort of patients given oromucosally administered Δ-THC and CBD to gain understanding in the strengths and weaknesses of the various detection methods.