Publications by authors named "Georgios Giannos"

Article Synopsis
  • The study focuses on developing a predictive model called SEAL to assess the risk of serious postoperative complications after emergency laparotomy (EL), aiming to improve patient management.
  • Researchers analyzed data from 633 patients and identified six key predictors for complications, demonstrating that SEAL has strong accuracy and calibration compared to the existing ACS-NSQIP model.
  • The SEAL model is seen as a valuable tool for personalized risk assessment, with suggestions for further testing in diverse environments to validate its effectiveness.
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Background: Accurate preoperative risk assessment in emergency laparotomy (EL) is valuable for informed decision making and rational use of resources. Available risk prediction tools have not been validated adequately across diverse health care settings. Herein, we report a comparative external validation of four widely cited prognostic models.

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Article Synopsis
  • - The study investigates the outcomes of emergency laparotomy (EL) in Greece, comparing results with the National Emergency Laparotomy Audit (NELA) to understand patient outcomes and mortality rates.
  • - Conducted from 01.2019 to 05.2020, the study included 633 patients in 11 Greek hospitals, revealing a 30-day post-operative mortality rate of 16.3% and identifying risk factors such as age, ASA class, and pre-existing health conditions.
  • - Results show that while patient demographics were similar between Greece and the UK, the Greek cohort had significantly higher mortality rates and lower ICU utilization, indicating a potential quality of care issue that may contribute to the worse outcomes.
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Objective: Infliximab, a tumour necrosis factor-α (TNFα) antagonist, has advanced the management of ulcerative colitis. Although efficacious, considerable percentage of patients are resistant to treatment. Accumulative inflammatory burden in long-term ulcerative colitis patients refractory to therapy increases the risk of developing colorectal cancer (CRC).

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Fistulae between the colon or the small intestine and the uterus are extremely rare as the uterus is a thick, muscular organ. Here, we present the case of a 74-year-old female presenting to our surgical department because of fecal vaginal discharge for the past few months, which proved to be caused by a combined colouterine and jejunouterine fistula due to chronic diverticulitis. Total abdominal hysterectomy with bilateral oophorectomy with en bloc resection of part of the jejunum and the sigmoid colon and primary anastomoses were performed.

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