Dosimetric comparison of Acuros BV and AAPM TG-43 formalism for interstitial iridium-192 high-dose-rate brachytherapy.

Purpose: The aim of this study was a retrospective dosimetric comparison of iridium-192 (Ir) high-dose-rate (HDR) interstitial brachytherapy plans using model-based dose calculation algorithm (MBDCA) following TG-186 recommendations and TG-43 dosimetry protocol for breast, head-and-neck, and lung patient cohorts, with various treatment concepts and prescriptions.

Material And Methods: In this study, 59 interstitial Ir HDR brachytherapy cases treated in our center (22 breast, 22 head and neck, and 15 lung) were retrospectively selected and re-calculated with TG-43 dosimetry protocol as well as with Acuros BV dose calculation algorithm, with dose to medium option based on computed tomography images. Treatment planning dose volume parameter differences were determined and their significance was assessed.