is best known for its significant adaptive potential and ability to colonize different ecological niches. Different strains of are widely used as probiotics. To characterize the probiotic potential of the novel FCa3L strain isolated from fermented cabbage, we sequenced its whole genome using the Illumina MiSeq platform.
View Article and Find Full Text PDFLactic acid bacteria are widespread in various ecological niches with the excess of nutrients and have reduced capabilities to adapt to starvation. Among more than 280 Lactobacillus species known to the date, only five, including Lactobacillus hilgardii, carry in their genome the gene encoding for PII-like protein, one of the central regulators of cellular metabolism generally responding to energy- and carbon-nitrogen status in many free-living Bacteria, Archaea and in plant chloroplasts. In contrast to the classical PII encoding genes, in L.
View Article and Find Full Text PDFThe frequency of mycoses caused by drug-resistant fungal pathogen has increased drastically over the last two decades. The spread of drug-resistant strains, along with the limitations of currently available antifungals, complicates the management of fungal infections, thereby representing great challenges for clinical healthcare. Among various antimicrobial pharmacophores, 2(5)-furanone derivatives have demonstrated antimicrobial, antifungal, and antibiofilm activities.
View Article and Find Full Text PDFAntimicrobial peptides (AMPs) are natural antagonistic tools of many bacteria and are considered as attractive antimicrobial agents for the treatment of bacteria with multidrug resistance. Lactic acid bacteria from the gastrointestinal tract of animals and human produce various AMPs inhibiting the growth of pathogens. Here we report the isolation and identification of novel Lactobacillus fermentum strain HF-D1 from the human gut producing AMPs which prevents the growth of P.
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