Publications by authors named "Georgia Papapavlou Lingehed"
Article Synopsis
- Multiple sclerosis (MS) is a disease that affects the brain and can improve during pregnancy, especially in the third trimester when women have fewer symptoms.
- Scientists studied T cells (a type of immune cell) from women with MS and healthy women before, during, and after pregnancy to understand how the disease changes.
- The study found that during pregnancy, especially in the third trimester, the T cells showed changes in their DNA and gene activity that helped protect against MS, but these changes went back to normal after childbirth.
Multiple sclerosis (MS) is a chronic autoimmune neuroinflammatory and neurodegenerative disorder of the central nervous system. Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3 trimester, followed by a transient exacerbation after delivery. Although the exact mechanisms behind the pregnancy-induced modulation are yet to be deciphered, it is likely that the immune tolerance established during pregnancy is involved.
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