Publications by authors named "Georgia Montone"

Article Synopsis
  • The study looked at how a heart procedure called TEER affects patients with different types of heart failure (HF) who also have a condition called mitral regurgitation (MR).
  • Over 162 patients were analyzed, and they found that people with mixed HF had worse health outcomes after the procedure compared to those with just systolic or diastolic HF.
  • The total hospital costs were similar for all groups, meaning no one type of heart failure cost significantly more than the others during their hospital stay.
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To develop risk scoring models predicting long-term survival and major adverse cardiovascular and cerebrovascular events (MACCEs), including myocardial infarction and stroke after coronary artery bypass grafting (CABG). All 4,821 consecutive patients who underwent isolated CABG at Lankenau between January 2005 and July 2021 were included. MACCE was defined as all-cause mortality + myocardial infarction + stroke.

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Purpose: To investigate the impact of direct aortic cannulation (DAC) versus femoral arterial cannulation (FAC) on clinical outcomes of surgery for acute type A aortic dissection.

Methods: PubMed/MEDLINE, Scopus, and Cochrane Central Register of Controlled Trials were searched until August 25, 2023, to conduct a meta-analysis. Primary endpoints of the study were operative mortality and postoperative stroke.

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Article Synopsis
  • The study analyzes the midterm clinical outcomes of robotic-assisted reverse hybrid coronary revascularization (HCR) in 285 patients over a period from 2005 to 2021.
  • The procedure involved stent implantation prior to robotic-assisted harvesting of the left internal thoracic artery, followed by anastomosis without any conversions to full sternotomy.
  • Results showed a low incidence of complications post-surgery, with midterm follow-up indicating a 10.9% all-cause mortality rate and 35.9% experiencing major cardiovascular events, suggesting that reverse HCR is safe and effective for multivessel coronary artery disease.
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Background: Patients who are not candidates for traditional coronary artery bypass grafting (CABG) and amenable only for percutaneous coronary intervention (PCI) with stents can receive the "gold standard" left internal thoracic artery (LITA) to left anterior descending artery (LAD) anastomosis through robotic-assisted CABG and PCI to non-LAD coronary targets.

Aims: We aimed to analyse clinical outcomes of robotic-assisted CABG.

Methods: A total of 2,280 consecutive patients who had undergone robotic-assisted CABG between May 2005 and June 2021 were included in our study.

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To analyze clinical and echocardiographic outcomes after transcatheter edge-to-edge repair (TEER) with mitral valve clip device (MitraClip-TM) for functional vs degenerative mitral valve regurgitation (MR). All consecutive 185 patients undergoing TEER between January 2019 and March 2023 were included in the study. A propensity-adjusted analysis investigated differences among functional vs degenerative MR mechanism groups.

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Background: To investigate the impact of Cryo Nerve Block with cryoICE™ device utilization, on post-operative pain in patients undergoing isolated coronary artery bypass grafting (CABG) through left thoracotomy.

Methods: All consecutive patients undergoing isolated CABG through left thoracotomy between July 2021 and July 2022 from a single surgeon were included in the study. Patients using the cryoICE™ device for nerve block were compared for baseline demographics and pre-operative characteristics with those that did not use the cryoICE™ device.

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A wide range of low oxidation state aluminum-containing cluster anions, LAln- (n = 1-14, L = N[Si(Me)3]2), were produced via reactions between aluminum cluster anions and hexamethyldisilazane (HMDS). These clusters were identified by mass spectrometry, with a few of them (n = 4, 6, and 7) further characterized by a synergy of anion photoelectron spectroscopy and density functional theory (DFT) based calculations. As compared to a previously reported method which reacts anionic aluminum hydrides with ligands, the direct reactions between aluminum cluster anions and ligands promise a more general synthetic scheme for preparing low oxidation state, ligated aluminum clusters over a large size range.

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Several low oxidation state aluminum-containing cluster anions, LAlH and LAl (n = 2-4, L = N[Si(Me)]), were produced via reactions between aluminum hydride cluster anions, AlH, and hexamethyldisilazane (HMDS). These clusters were characterized by mass spectrometry, anion photoelectron spectroscopy, and density functional theory (DFT) based calculations. Agreement between the experimental and theoretical vertical detachment energies (VDEs) and adiabatic detachment energies (ADEs) validated the computed geometrical structures.

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