Resting beat-to-beat blood pressure variability in humans: role of alpha-1 adrenergic receptors.

Purpose: Resting beat-to-beat blood pressure variability is a strong predictor of cardiovascular events and mortality. However, its underlying mechanisms remain incompletely understood. Given that the sympathetic nervous system plays a pivotal role in cardiovascular regulation, we hypothesized that alpha-1 adrenergic receptors (the main sympathetic receptor controlling peripheral vasoconstriction) may contribute to resting beat-to-beat blood pressure variability.

Effects of triceps surae fatigue and weight training level on gait variability and local stability in young adults.

Muscle fatigue negatively affects gait, and the changes in gait pattern due to muscle fatigue is influenced by which muscles are fatigued and pre-existing physical activity levels. However, how these factors alter gait stability and variability, measures related to risk of fall, remains unclear. To explore how muscular fatigue affects linear and nonlinear gait features in young adults, the effects of triceps surae fatigue and weight training level on gait variability and local stability, as well as a 12-min recovery time of post-fatigue period, were evaluated in young adults (trained and untrained groups).