Direct O mediated oxidation of a Ni(II)NO structural model complex for the active site of nickel acireductone dioxygenase (Ni-ARD): characterization, biomimetic reactivity, and enzymatic implications.

A new biomimetic model complex of the active site of acireductone dioxygenase (ARD) was synthesized and crystallographically characterized (ii1). 1 displays carbon-carbon oxidative cleavage activity in the presence of O towards the substrate 2-hydroxyacetophenone. This reactivity was monitored UV-Visible and NMR spectroscopy.