ALK Mutation Status in EGFR-negative Non-small-cell Lung Cancer Patients in Bulgaria.

Background: Patients with non-small-cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK) rearrangement mutation are found to be 3-13%.

Aim: To evaluate the prevalence of ALK mutations in EGFR-negative NSCLC patients in Bulgaria.

Materials And Methods: One hundred and thirty-two patients with EGFR-negative NSCLC were examined for ALK mutation analysis between January and June 2016.