Publications by authors named "Georgi Hristov Vasilev"
Article Synopsis
- Despite the proven safety and effectiveness of COVID-19 vaccines, concerns persist among high-risk groups, particularly those with a history of blood clotting or bleeding issues.
- The review examines various genetic and acquired blood disorders, their potential interactions with the immune response to vaccination, and the available safety data related to these vaccines.
- It concludes that while there are rare instances of bleeding and thrombotic events, these do not demonstrate a direct cause-and-effect relationship with the COVID-19 vaccines, reinforcing the need for vaccination as a priority over minimal risks.
Pregnancy with SARS-CoV-2 infection can raise the risk of many complications, including severe COVID-19 and maternal-fetal adverse outcomes. Additionally, endothelial damage occurs as a result of direct SARS-CoV-2 infection, as well as immune system, cardiovascular, and thrombo-inflammatory reactions. In this narrative review, we focus on endothelial dysfunction (ED) in pregnancy, associated with obstetric complications, such as preeclampsia, fetal growth retardation, gestational diabetes, etc.
View Article and Find Full Text PDFIntroduction: Data on the associations between capillaroscopic changes and diagnostic systemic-sclerosis (SSc)-related antibodies are scarce. Presence of such correlation would improve current knowledge about the disease’s pathogenesis by revealing the mechanisms of microangiopathy. The microvascular pathology of SSc is a hallmark of the disease, and immunological abnormalities probably contribute to its development.
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