Publications by authors named "Georgescu D"

: Lower extremity amputations (LEAs) represent a significant health problem. The aim of our study was to analyse the type and trends of diabetes-related LEAs in patients hospitalized in one surgical centre in Bucharest between 2018 and 2021. The second aim was to assess the impact of the COVID-19 pandemic on the trends of LEAs.

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: Heart failure is associated with high morbidity and mortality and linked with several pre-existing health conditions and risk factors. Early detection and prompt management in heart failure improves patient outcomes. Liver involvement is associated with heart failure disease progression, and hence liver biomarkers and liver fibrosis may have a prognostic impact.

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Significant advances in the diagnosis and treatment of gastrointestinal diseases have been made in recent years [...

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The possible authorisation of new monoclonal antibody therapies for Alzheimer's disease poses challenges for healthcare systems worldwide. In this paper, the Swiss Memory Clinics association (SMC) analyses the available resources and identifies potential health care shortages. Overcoming potential bottlenecks is a challenge that requires action at various levels.

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: Renal lithiasis continues to represent a great challenge for modern urology in terms of minimally invasive management of lithotripsy procedures. The recent revolution of endoscopes with the miniaturization of instruments and the development of improved disposable ureteroscopes combined with recent suction methods such as suction access sheaths or direct in-scope suction (DISS) systems promise to further improve the outcome of renal stone treatment. : Considering this technological advance, this study aims to evaluate the results obtained by combining these methods in three groups: Group 1-Single-use 7.

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Introduction: Colorectal cancer stands as a predominant cause of cancer-related mortality worldwide. Despite progressive strides in surgical methodologies, the specter of postoperative complications is very large, significantly impacting both morbidity and mortality rates. This review aims to meticulously examine existing scholarly works to gauge the prevalence, severity, and therapeutic approaches to postoperative complications arising from colorectal cancer surgeries.

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  • Nailfold capillaroscopy is a test that checks small blood vessels in the fingers to see how well they're working, especially in people with rheumatoid arthritis (RA).
  • People with RA have a higher chance of heart problems, so the study looked at how their small blood vessels were doing before and after a year of treatment with a specific medicine called anti TNF-alpha.
  • The results showed that after the treatment, the small blood vessels in RA patients worked better, which means the medicine helped improve their condition!
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  • The study aimed to identify factors associated with poor and improved quality of life scores (QoSL) for patients with endometriosis, while also evaluating pain symptoms after surgical excision of rectovaginal nodules.
  • It involved 116 patients who underwent laparoscopic surgery, with assessments conducted pre-surgery and two years later using specific quality of life scoring systems (EHP-30 Module C).
  • Results showed significant improvements in QoSL and pain levels, particularly with complete excision of nodules leading to better outcomes compared to incomplete excision.
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Introduction The SARS-CoV-2 virus causes the highly contagious coronavirus disease 2019 (COVID-19), which most commonly manifests as severe acute respiratory syndrome. The virus is part of the Coronaroviridae family, a group of viruses that can cause various diseases, such as the common cold, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). The World Health Organization (WHO) declared the outbreak of COVID-19 as a pandemic on March 11, 2020.

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  • The prevalence of atrial fibrillation (AF) has increased over the past 20 years, making it the most common heart rhythm disorder, thus requiring more in-hospital management for patients experiencing acute issues.
  • Research indicates that a higher neutrophil-to-lymphocyte ratio (NLR) can predict in-hospital mortality, suggesting it could serve as an important biomarker for patient outcomes.
  • A study at a medical clinic analyzed 1111 patients admitted for AF and found that those who died had a significantly higher NLR at admission compared to survivors, confirming that NLR is an independent predictor of in-hospital death.
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Introduction: Urolithiasis is a serious health issue that is constantly getting worse around the world. In relation to laser lithotripsy, new techniques and technological advancements have emerged, giving urologists a wide range of choices for treating stone disease. The objective of the present review is to provide an overview of the most current developments and show how effective they are for reducing complications and boosting surgical effectiveness.

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  • Sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) is a rare but serious liver condition often linked to chemotherapy and bone marrow transplants, characterized by signs of portal hypertension.
  • The case discusses a 65-year-old woman who experienced symptoms like fatigue, abdominal tenderness, and elevated liver enzymes after undergoing chemotherapy for colorectal cancer with liver metastases.
  • Despite the diagnosis being complicated by her recent endometrial cancer treatment, timely identification of SOS/VOD is crucial for managing risks and improving patient outcomes.
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The intercondylar notch (ICN) is an important element of knee morphometry, in close relation to the anterior cruciate ligament (ACL). To find the average are of the anterior notch in each ICN specific shape (A-, W-, or U-shape). Magnetic resonance imaging (MRI) scans were independently analyzed by two experts, one orthopedic surgeon and one imaging physician.

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In this paper, we study the influence of densified microsilica and colloidal nanosilica admixtures on the mechanical strength and the microstructural characteristics of special mortars used for immobilizing radioactive concrete waste. The experimental program focused on the replacement of cement with micro- and/or nanosilica, in different proportions, in the basic composition of a mortar made with recycled aggregates. The technical criteria imposed for such cementitious systems, used for the encapsulation of low-level radioactive waste, imply high fluidity, increased mechanical strength and lack of segregation and of bleeding.

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  • A study involving 300 participants, including dyslipidemic patients on and off statins and healthy controls, aimed to explore the connection between long-term statin use, gallstone disease (GSD), and gut microbiota differences.
  • Results showed that gut dysbiosis was more prevalent in statin-negative patients, and GSD was less common in those on statins, suggesting a protective effect.
  • Significant correlations were found between GSD and conditions like obesity and diabetes, with gut dysbiosis and obesity identified as independent risk factors for GSD among statin patients.
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Introduction: During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, the management of patients with lower urinary tract symptoms (LUTS) underwent dynamic adjustments in response to an evolving understanding of the virus's impact on different patient populations. Healthcare practitioners reevaluated therapeutic approaches for conditions like benign prostatic hyperplasia (BPH), considering the potential implications of this condition on the severity and progression of coronavirus disease 2019 (COVID-19). This study aims to investigate potential correlations between SARS-CoV-2 infection severity, exacerbation of LUTS, and BPH progression.

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Since we aim to test new options to find medication for cognitive disorders, we have begun to assess the effect of semaglutide and to conduct a review gathering studies that have attempted this purpose. This systematic review focuses on the cognitive effects of semaglutide, a glucagon-like peptide 1 receptor agonist (GLP-1 RA), in the context of neurological and cognitive impairment. Semaglutide, a synthetic GLP-1 analog, showcased neuroprotective effects beyond metabolic regulation.

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Cryptorchidism is defined as the extra-scrotal position of the testes. It is a common disorder in male children, but rarely in adult patients. The association of cryptorchidism with hernia is a common finding in childhood, but is not frequent in adults or the elderly.

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As laparoscopy gained global popularity in oncologic surgery, the challenge of detecting lymph nodes spurred researchers to explore innovative techniques and approach the situation from a fresh perspective. While many proposed methods have faded into obscurity, the utilization of indocyanine green (ICG) in the surgical treatment of oncologic patients has continued to advance. The immense potential of this dye is widely acknowledged, yet its full extent and limitations in lymphatic mapping for colorectal cancer remain to be precisely determined.

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The «Recommendations for the Diagnosis and Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD)» were developed in parallel with the Swiss National Dementia Strategy 2014-2019 under the auspices of the Swiss Society for Geriatric Psychiatry and Psychotherapy (SGAP) and mark the beginning of a series of recommendations for geriatric psychiatric disorders. They depict the evidence-based state of knowledge about diagnostics and therapy, based on the clinical experience of the experts, and are designed for interprofessional and interdisciplinary use. The non-pharmacological intervention options and pharmacotherapy are discussed in detail.

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  • Palliative radiotherapy is an important treatment for symptom relief in women with various gynecological cancers, including cervical, endometrial, ovarian, vaginal, and vulvar cancers.
  • A comprehensive review of literature revealed that while many studies focused on outcomes like symptom relief and quality of life, results were inconsistent and often limited by lack of standardized measures.
  • Despite challenges in measuring overall effectiveness, the review found positive results for pain control and bleeding management, suggesting that further research is needed to optimize treatment regimens and improve patient outcomes.
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Ectopic pregnancies are a frequently encountered cause of first-trimester metrorrhagia. They occur when an embryo is implanted and grows outside the normal uterine space. Uncommonly, the embryo can be implanted in the intramural portion of the uterine tube, a condition referred to as interstitial localization.

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Objectives: Our aim was to report an anatomic model of an autologous flap based on the internal thoracic blood supply: the pedicled thoraco-chondro-costal flap; and establish the feasibility of various types of extended tracheal replacement with this novel flap, according to a newly proposed topographic classification.

Methods: In a cadaveric model, a cervicotomy combined with median sternotomy was performed. The incision was extended laterally to expose the chest wall.

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