Publications by authors named "Georges Nassrallah"

Purpose: This study aims to identify clinical similarities and differences between males and females presenting with orbital fracture.

Methods: Patient charts of adult orbital fracture cases diagnosed via computed tomography and referred by a level 1 trauma center to the McGill University Health Centre between August 2015 to January 2018 were examined and analyzed. Clinical parameters included age, sex, mechanism of injury, morphology of orbital fracture, symptoms and examination features, and rates of ocular pathology.

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Objective: To assess the prevalence of unintended placement of intraocular lens (IOL) haptics in the sulcus and its association with posterior capsular opacification (PCO).

Design: Cross-sectional study.

Participants: 428 post-mortem pseudophakic human eyes.

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Mitomycin C is an alkylating agent with the ability to suppress fibroblast proliferation and activity, making it a powerful antifibrotic. It has therefore become popular in glaucoma filtering surgeries, used both intraoperatively during bleb formation and postoperatively as an adjunct to bleb needling. This report presents a rare but serious risk of bleb needling with Mitomycin C at the slit lamp, where inadvertent movement of the patient resulted in an orbital injection.

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Article Synopsis
  • A 68-year-old woman had a concerning eye lesion initially thought to be an atypical fibroxanthoma, but it was later diagnosed as spindle cell carcinoma after a biopsy.
  • Spindle cell carcinoma is a rare and aggressive type of squamous cell carcinoma, highlighting the need for careful surgical technique and comprehensive analysis for accurate diagnosis.
  • The case contributes to limited research on this type of cancer affecting the eye, aiming to improve future diagnostic and treatment guidelines as more data becomes available.
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Objective: To evaluate the capsulorrhexis structure in postmortem eyes and determine factors associated with posterior capsular opacification (PCO).

Design: Experimental study.

Participants: Postmortem pseudophakic human eyes (n = 420).

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Introduction: To determine whether the two popular artificial intelligence chatbots, ChatGPT and Bard, can provide high-quality information concerning procedure description, risks, benefits, and alternatives of various ophthalmic surgeries.

Methods: ChatGPT and Bard were prompted with questions pertaining to the description, potential risks, benefits, alternatives, and implications of not proceeding with various surgeries in different subspecialties of ophthalmology. Six common ophthalmic procedures were included in the authors' analysis.

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Article Synopsis
  • This case report details a 20-year-old woman who developed serious complications, including orbital compartment syndrome and peripheral neuropathy, following a vitrectomy surgery for retinal detachment.
  • The patient's symptoms included significant eye movement issues and facial abnormalities due to extensive gas accumulation in the orbit and surrounding areas, which were confirmed by a CT scan.
  • Urgent surgical intervention through lateral canthotomy and cantholysis was performed, leading to resolution of most symptoms, and the patient achieved improved vision by week 7 post-surgery.
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Objective: This study aims to objectively measure the degree of zonular dehiscence in postmortem eyes and to assess for clinical and anatomic correlates.

Design: Cross-sectional study.

Materials: Four hundred and twenty-seven postmortem pseudophakic human eyes.

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Purpose: The Isabel differential diagnosis generator is one of the most widely known electronic diagnosis decision support tools. The authors prospectively evaluated the utility of Isabel for orbital disease differential diagnosis.

Methods: The terms "proptosis," "lid retraction," "orbit inflammation," "orbit tumour," "orbit tumor, infiltrative" and "orbital tumor, well-circumscribed" were separately input into Isabel and the results were tabulated.

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Article Synopsis
  • This study investigates the patterns, reasons, and diagnostic accuracy of referrals to an emergency ophthalmology consultation service from emergency departments and optometrists over a one-year period.
  • It found that both EDs and optometrists most frequently referred patients for vitreoretinal and corneal issues, but optometrists had a significantly higher diagnostic accuracy.
  • The findings highlight the potential for better collaboration between optometrists and ophthalmologists to reduce wait times and improve patient care.
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Purpose: Ocular pathology (OP) following orbital fracture can vary vastly in complexity and severity. Extra-ocular motility (EOM) limitations are frequently present in orbital trauma cases, with patterns of duction limitations being symmetrical or asymmetrical. The aim of this study was to identify if there was any association between increased OP following orbital fracture cases based on the pattern of EOM deficits.

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Purpose: To describe a transconjunctival technique for full-thickness (excisional) optic nerve biopsy.

Method: A medial transconjunctival approach to the optic nerve with disinsertion of the medial rectus is used. A small right-angle Mixter forcep is used to clamp the optic nerve far posteriorly, and then a microscalpel is directed metal-on-metal to cut the posterior optic nerve.

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Objective: Subconjunctival hemorrhage (SCH) is a common presentation in patients with orbital trauma and often warrants investigation of underlying ocular pathology. Our study aims to assess the significance of SCH severity, graded in a spatial 0-360° manner, as a predictor for ocular pathology in patients with orbital fracture.

Design: Retrospective chart review.

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Objective: With increasing constraints on our publicly funded health care system, appropriate triage of trauma patients is becoming pivotal, making the primary care assessment (PCA) invaluable. Our study aims to compare the initial assessment of patients with orbital fractures with that conducted by the ophthalmology service.

Design: Retrospective chart review.

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Purpose: Upper lid eversion in adults from non-cicatricial causes is rare. We report a case of upper eyelid eversion secondary to epidemic keratoconjunctivitis (EKC).

Observations: A 37 year-old female presented with unilateral upper lid eversion.

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Objective: The aim of this study is to examine the quality of life (QOL) outcomes of patients undergoing different uveal melanoma (UM) treatments and to appraise the literature on the topic.

Design And Participants: A systematic review was conducted to address the study objective. Patients undergoing UM treatment with or without metastasis were eligible for inclusion in this review.

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Objective: Retrobulbar hemorrhage (RBH) is a potentially sight-threatening complication of orbital fractures causing an orbital compartment syndrome (OCS). RBH causing OCS is regarded as a clinical diagnosis when evidence of optic nerve compression is found. Nonetheless, many patients with facial trauma will have received imaging by computed tomography (CT) on which there is documented RBH, with or without signs of OCS.

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Purpose: We report the case of a patient with cavernous sinus syndrome associated with biopsy-confirmed metastasis from colorectal cancer.

Observations: A patient known for laryngeal carcinoma and metastatic colorectal carcinoma presented with symptoms of left trigeminal neuralgia and progressive, near-complete ophthalmoplegia. Magnetic resonance imaging (MRI) revealed a mass in the left cavernous sinus, extending into Meckel's cave with perineural spread along the mandibular branch of the left trigeminal nerve.

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Purpose: This article is a continuation of a qualitative study designed to explore how radiology exposures can impact medical student opinions and perceptions of radiology and radiologists. We focused on: 1) conducting a radiology exposure inventory from the perspective of the medical student; 2) student evaluation of the quality of the radiology exposures and suggestions for positive change; and 3) development of a framework to address the needs of medical students as it relates to radiology education in the undergraduate medical curriculum.

Methods: Research methodology and design for this qualitative study were described in detail in a previous article by Visscher et al [1].

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