Publications by authors named "Georges F Vles"

The clinical implementation of currently used devices for intraoperative fixation monitoring of femoral implants via vibration-based methods in cementless total hip arthroplasty is challenging, due to practical and regulatory issues. Motivated by the effectiveness of electromagnetic excitation in similar dental applications, this study investigates the use of electromagnetic excitation for femoral implant stability monitoring during cementless total hip arthroplasty. The results obtained from electromagnetic excitation were largely consistent with reference results obtained through impact excitation, with a Pearson Correlation Coefficient of 0.

View Article and Find Full Text PDF

Orthopedic-device-related infections (ODRIs) are challenging clinical complications that are often exacerbated by antibiotic resistance and biofilm formation. This review explores the efficacy of naturally occurring antimicrobials - including agents sourced from bacteria, fungi, viruses, animals, plants and minerals - against pathogens common in ODRIs. The limitations of traditional antibiotic agents are presented, and innovative naturally occurring antimicrobials, such as bacteriophage therapy and antimicrobial peptides, are evaluated with respect to their interaction with conventional antibiotics and antibiofilm efficacy.

View Article and Find Full Text PDF

Introduction: Klippel-Trenaunay syndrome (KTS) affects the development of blood vessels, soft tissues (such as skin and muscles), and bone. It is a rare cause of severe degenerative joint disease at an early age. Orthopedic interventions in these patients bring numerous difficulties for various reasons.

View Article and Find Full Text PDF

Background: Total hip arthroplasty (THA) for avascular necrosis (AVN) or inflammatory arthritis (IA) comes with a relatively high risk of aseptic stem loosening, especially in young patients. There are limited long-term data on the survivorship of polished, tapered, cemented stems in this population. We therefore performed a single-center retrospective study investigating the survival of this particular stem type in young patients with AVN or IA.

View Article and Find Full Text PDF

Although mechanical alignment (MA) has traditionally been considered the gold standard, the optimal alignment strategy for total knee arthroplasty (TKA) is still debated.Kinematic alignment (KA) aims to restore native alignment by respecting the three axes of rotation of the knee and thereby producing knee motion more akin to the native knee.Designer surgeon case series and case control studies have demonstrated excellent subjective and objective clinical outcomes as well as survivorship for KA TKA with up to 10 years follow up, but these results have not been reproduced in high-quality randomized clinical trials.

View Article and Find Full Text PDF

Objective: The aim of the study was to design an objective, transparent, pragmatic, and flexible workflow to assist with patient selection during the initial phase of return to elective orthopedic surgery during the COVID-19 pandemic with the main purpose of enhancing patient safety.

Methods: A multidisciplinary working group was formed consisting of representatives for orthopedics, epidemiology, ethics, infectious diseases, cardiovascular diseases, and intensive care medicine. Preparation for upcoming meetings consisted of reading up on literature and testing of proposed methodologies on our own waiting lists.

View Article and Find Full Text PDF

Aims: One of the instruments in the orthopaedic surgeon's armamentarium to face the challenges associated with periprosthetic fracture around the stem of a hip replacement is the tapered, fluted, modular, titanium (TFMT) stem. Our aim was to study its clinical and radiological outcomes.

Patients And Methods: During the period 2010-2016 86 patients (55 females; median age 78.

View Article and Find Full Text PDF

Skeletal muscle plasticity is reflected by a dynamic balance between protein synthesis and breakdown, with basal muscle tissue protein synthesis rates ranging between 0.02 and 0.09%/h.

View Article and Find Full Text PDF

Background: Carbon-fiber-reinforced Polyetheretherketone (CFR-PEEK) nails are gaining interest as they have biomechanical properties potentially capable of overcoming disadvantages of conventional metal nails.

Case Summary: Three cases are illustrated which required superior mechanical toughness, compatibility with radiotherapy, and postoperative advanced imaging.

Conclusion: CFR-PEEK nails seem to have a niche role in distinct groups of patients.

View Article and Find Full Text PDF

We report the case of a 64-year-old fanatic female walker who presented with pain of her right distal tibia. MRI and bone scan showed a horizontal stress fracture of the distal tibia which was treated conservatively by means of cast immobilisation.

View Article and Find Full Text PDF

A 76-year-old man visited the Emergency Room because of pain of a progressive, swelling of his right lower leg that had developed 69 years ago after a posttraumatic compartment syndrome. We performed debridement on the necrotic, infected wound and made the diagnosis 'calcific myonecrosis'.

View Article and Find Full Text PDF

Background: Little is known about the long-term effects of Continuous intrathecal Baclofen (CITB) therapy in non-ambulant children with intractable spastic Cerebral Palsy (CP).

Aim: To determine whether short-term beneficial effects of CITB therapy are present at the long-term, and whether caregivers would choose CITB therapy for their child again considering the advantages and disadvantages encountered over the years.

Methods: Long-term follow-up data were obtained of the children whom had previously participated in a RCT on CITB by the Dutch Study Group on Spasticity.

View Article and Find Full Text PDF

Background: Cerebral palsy (CP) may cause severe spasticity, requiring neurosurgical procedures. The most common neurosurgical procedures are continuous infusion of intrathecal baclofen and selective dorsal rhizotomy. Both are invasive and complex procedures.

View Article and Find Full Text PDF

Objective: This study examined the reliability and efficiacy of the Visual Analogue Scale (VAS) in evaluating spasticity treatment in an outpatient setting.

Patients And Methods: We used a parent-reported VAS device for evaluating the effects of Botulinum Toxin A (BTX-A). Data were collected on 55 children with cerebral palsy.

View Article and Find Full Text PDF