Publications by authors named "George Yiadom Osei"
Colorectal cancer (CRC) is a significant contributor to cancer mortality worldwide, and the presence of cancer stem cells (CSC) represents a major challenge for achieving effective treatment. miRNAs have emerged as critical regulators of gene expression, and recent studies have highlighted their role in regulating stemness and therapeutic resistance in CRC stem cells. This review highlights the mechanisms of CSC development, therapy resistance and the potential of miRNAs as therapeutic targets for CRC.
View Article and Find Full Text PDFColorectal cancer (CRC) is a serious global health concern, with a high incidence and mortality rate. Although there have been advancements in the early detection and treatment of CRC, therapy resistance is common. MicroRNAs (miRNAs), a type of small non-coding RNA that regulates gene expression, are key players in the initiation and progression of CRC.
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- The study focused on vulvovaginal candidiasis (VVC) among pregnant women, finding a prevalence rate of 30.7% and identifying Candida glabrata as the most common species.
- It involved analyzing 176 high vaginal swab samples from pregnant women using culture and susceptibility tests for various antifungal drugs, assessing resistance patterns.
- Results demonstrated that 50% of Candida species were susceptible to voriconazole, while resistance was notably high for fluconazole and nystatin, suggesting a need for effective treatment strategies.
Background: Malaria is known to cause severe health consequences due to its marked effects and alteration on the haematological parameters of infected individuals. This study evaluated the haematological profile of adult individuals infected with the malaria parasite.
Methods: A retrospective study was conducted using archived data of malaria positive cases from January 2017 to March 15, 2019.