Antiphospholipid antibodies before and after liver transplantation.

Objective: The aim of this study was to determine whether liver transplantation of patients with antiphospholipid antibodies (APA) is 1) adversely affected with vascular thrombosis and 2) whether such antibodies persist post transplantation.

Methods: Twelve patients with APA awaiting transplant were identified and characterized biochemically and immunologically. Each had the level of APA determined using commercially available enzyme-linked immunoassay kits before, during, and after liver transplantation.

Hemostatic modulation with the liver dialysis device in humans with advanced liver disease.

Background/aims: To determine the alterations in coagulation and fibrinolysis occurring in patients treated with the liver dialysis device.

Methodology: Patients with advanced liver disease treated with the liver dialysis device were studied immediately before and after the liver dialysis device treatment.

Setting: A university hospital intensive care unit.