Publications by authors named "George T De Sanctis"
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Synopsis of recent research by authors named "George T De Sanctis"
George T De Sanctis' research primarily focuses on the mechanisms underlying respiratory diseases, particularly in relation to inflammation, airway hyperresponsiveness, and the impact of various environmental factors such as ozone and wood smoke on pulmonary health.
His work has revealed important insights into the roles of key proteins and inflammatory mediators, such as cathepsin S and nitric oxide synthase-2 (NOS2), in regulating lung responses to allergens and irritants, contributing to our understanding of conditions like asthma and chronic obstructive pulmonary disease (COPD).
The research highlights the complex interactions between immune responses and airway inflammation, suggesting potential therapeutic targets for improving outcomes in patients with respiratory conditions exacerbated by environmental exposures.