Temporal Lobe Encephalocele with Epilepsy in A Young Female: An Atypical Presentation of Idiopathic Intracranial Hypertension.

Idiopathic intracranial hypertension (IIH) is typically described in a middle-aged female and present with symptoms of headache, transient visual obscuration, photophobia, diplopia, rarely with pulsatile tinnitus. Seizure as a sole manifestation is very rare. Here we present a case of a young non-obese female with epilepsy, and imaging revealed temporal lobe encephalocele with typical imaging features of IIH.

Role of epigenetics in unicellular to multicellular transition in Dictyostelium.

Background: The evolution of multicellularity is a critical event that remains incompletely understood. We use the social amoeba, Dictyostelium discoideum, one of the rare organisms that readily transits back and forth between both unicellular and multicellular stages, to examine the role of epigenetics in regulating multicellularity.

Results: While transitioning to multicellular states, patterns of H3K4 methylation and H3K27 acetylation significantly change.